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Supakarn Chamni

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Articles 46
Citations 329
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Recent Articles
1.
Sanachai K, Chamni S, Nutho B, Khammuang S, Ratha J, Choowongkomon K, et al.
Mol Divers . 2025 Feb; PMID: 39994156
α-Glucosidase inhibitors (AGIs) are pharmacological agents commonly used to manage postprandial hyperglycemia associated with type 2 diabetes mellitus (T2DM). Developing novel, potent AGIs remains a significant area of research. In...
2.
Sanachai K, Hengphasatporn K, Chamni S, Suwanborirux K, Mahalapbutr P, Shigeta Y, et al.
Comput Biol Chem . 2025 Jan; 115:108346. PMID: 39824143
Janus kinases (JAKs) are a family of intracellular tyrosine kinases that play a crucial role in signal transduction pathways. JAK2 has been implicated in the pathogenesis of leukemia, making it...
3.
Sumrejkanchanakij P, Fitri A, Pavasant P, Chareonvit S, Lin A, Chamni S
Arch Oral Biol . 2025 Jan; 172:106175. PMID: 39813772
Objective: Asiaticoside has the capacity to induce osteogenic differentiation of human periodontal ligament cells (hPDLCs) through Wnt (Wingless-related integration site) signaling. A modified chemical structure (by removing glycoside side chain),...
4.
Pojtanadithee P, Isswanich K, Buaban K, Chamni S, Wilasluck P, Deetanya P, et al.
Biophys Chem . 2024 Nov; 304:107125. PMID: 39491914
Drug development requires significant time and resources, and computer-aided drug discovery techniques that integrate chemical and biological spaces offer valuable tools for the process. This study focused on the field...
5.
Visuthranukul C, Sriswasdi S, Tepaamorndech S, Chamni S, Leelahavanichkul A, Joyjinda Y, et al.
Int J Obes (Lond) . 2024 Jul; 48(12):1696-1704. PMID: 39033197
Background And Objectives: Gut dysbiosis that resulted from the alteration between host-microbe interaction might worsen obesity-induced systemic inflammation. Gut microbiota manipulation by supplementation of prebiotic inulin may reverse metabolic abnormalities...
6.
Suroengrit A, Cao V, Wilasluck P, Deetanya P, Wangkanont K, Hengphasatporn K, et al.
Heliyon . 2024 Jun; 10(11):e31987. PMID: 38867992
Background: Anti-SARS-CoV-2 and immunomodulatory drugs are important for treating clinically severe patients with respiratory distress symptoms. Alpha- and gamma-mangostins (AM and GM) were previously reported as potential 3C-like protease (3CL)...
7.
Visuthranukul C, Leelahavanichkul A, Tepaamorndech S, Chamni S, Mekangkul E, Chomtho S
Sci Rep . 2024 May; 14(1):11181. PMID: 38755201
Gut microbiota manipulation may reverse metabolic abnormalities in obesity. Our previous studies demonstrated that inulin supplementation significantly promoted Bifidobacterium and fat-free mass in obese children. We aimed to study gut-muscle...
8.
Myint S, Laomeephol C, Thamnium S, Chamni S, Luckanagul J
Pharmaceutics . 2023 Dec; 15(12). PMID: 38140012
Hyaluronic acid (HA) nanogels are a versatile class of nanomaterials with specific properties, such as biocompatibility, hygroscopicity, and biodegradability. HA nanogels exhibit excellent colloidal stability and high encapsulation capacity, making...
9.
Buaban K, Innets B, Petsri K, Sinsook S, Chanvorachote P, Chansriniyom C, et al.
Sci Rep . 2023 Dec; 13(1):21485. PMID: 38057385
The semisynthesis of 5-O-ester derivatives of renieramycin T was accomplished through the photoredox reaction of renieramycin M (1), a bistetrahydroisoquinolinequinone alkaloid isolated from the Thai blue sponge Xestospongia sp. This...
10.
Soe H, Junthip J, Chamni S, Chansriniyom C, Limpikirati P, Thanusuwannasak T, et al.
Int J Pharm . 2023 Sep; 645:123394. PMID: 37689255
Effective antifungal therapy for the treatment of fungal keratitis requires a high drug concentration at the corneal surface. However, the use of natural β-cyclodextrin (βCD) in the preparation of aqueous...