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» Authors » Khanit Suwanborirux

Khanit Suwanborirux

Explore the profile of Khanit Suwanborirux including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 74
Citations 548
Followers 0
Related Specialties
Pharmacology
Microbiology
Biology
Top 10 Co-Authors
Naoki Saito
Somboon Tanasupawat
Pithi Chanvorachote
Supakarn Chamni
Takuji Kudo
Chitti Thawai
Wongsakorn Phongsopitanun
Kornkanok Ingkaninan
Natchanun Sirimangkalakitti
Moriya Ohkuma
Published In
Int J Syst Evol Microbiol
J Nat Prod
Mar Drugs
Anticancer Res
Chem Pharm Bull (Tokyo)
Affiliations
Soon will be listed here.
Recent Articles
1.
Exploring mimosamycin as a Janus kinase 2 inhibitor: A combined computational and experimental investigation
Sanachai K, Hengphasatporn K, Chamni S, Suwanborirux K, Mahalapbutr P, Shigeta Y, et al.
Comput Biol Chem . 2025 Jan; 115:108346. PMID: 39824143
Janus kinases (JAKs) are a family of intracellular tyrosine kinases that play a crucial role in signal transduction pathways. JAK2 has been implicated in the pathogenesis of leukemia, making it...
2.
Semisynthesis of 5-O-ester derivatives of renieramycin T and their cytotoxicity against non-small-cell lung cancer cell lines
Buaban K, Innets B, Petsri K, Sinsook S, Chanvorachote P, Chansriniyom C, et al.
Sci Rep . 2023 Dec; 13(1):21485. PMID: 38057385
The semisynthesis of 5-O-ester derivatives of renieramycin T was accomplished through the photoredox reaction of renieramycin M (1), a bistetrahydroisoquinolinequinone alkaloid isolated from the Thai blue sponge Xestospongia sp. This...
3.
Light-Mediated Transformation of Renieramycins and Semisynthesis of 4'-Pyridinecarbonyl-Substituted Renieramycin-Type Derivatives as Potential Cytotoxic Agents against Non-Small-Cell Lung Cancer Cells
Sinsook S, Buaban K, Iksen I, Petsri K, Innets B, Chansriniyom C, et al.
Mar Drugs . 2023 Jul; 21(7). PMID: 37504931
The semisynthesis of renieramycin-type derivatives was achieved under mild and facile conditions by attaching a 1,3-dioxole-bridged phenolic moiety onto ring A of the renieramycin structure and adding a 4'-pyridinecarbonyl ester...
4.
Transformation of Renieramycin M into Renieramycins T and S by Intramolecular Photoredox Reaction of 7-Methoxy-6-methyl-1,2,3,4-tetrahydroisoquinoline-5,8-dione Derivatives
Yokoya M, Yamazaki-Nakai M, Nakai K, Sirimangkalakitti N, Chamni S, Suwanborirux K, et al.
J Nat Prod . 2023 Jan; 86(1):222-231. PMID: 36631738
In connection with our studies of biologically active 1,2,3,4-tetrahydroisoquinoline marine natural products, we describe herein a useful intramolecular photoredox transformation of 7-methoxy-6-methyl-1,2,3,4-tetrahydroisoquinoline-5,8-dione tricyclic models into 5-hydroxy-tetrahydroisoquinol[1,3]dioxoles in excellent yields. We...
5.
5--(-Boc-l-Alanine)-Renieramycin T Induces Cancer Stem Cell Apoptosis via Targeting Akt Signaling
Suksamai D, Racha S, Sriratanasak N, Chaotham C, Aphicho K, Lin A, et al.
Mar Drugs . 2022 Apr; 20(4). PMID: 35447911
Cancer stem cells (CSCs) drive aggressiveness and metastasis by utilizing stem cell-related signals. In this study, 5--(-Boc-l-alanine)-renieramycin T (OBA-RT) was demonstrated to suppress CSC signals and induce apoptosis. OBA-RT exerted...
6.
22-O-(N-Boc-L-glycine) ester of renieramycin M inhibits migratory activity and suppresses epithelial-mesenchymal transition in human lung cancer cells
Oo Y, Nealiga J, Suwanborirux K, Chamni S, Ecoy G, Pongrakhananon V, et al.
J Nat Med . 2021 Jul; 75(4):949-966. PMID: 34287745
The incidence of metastasis stage crucially contributes to high recurrence and mortality rate in lung cancer patients. Unfortunately, no available treatment inhibits migration, a key metastasis process in lung cancer....
7.
Jorunnamycin A Suppresses Stem-Like Phenotypes and Sensitizes Cisplatin-Induced Apoptosis in Cancer Stem-Like Cell-Enriched Spheroids of Human Lung Cancer Cells
Sumkhemthong S, Chamni S, Ecoy G, Taweecheep P, Suwanborirux K, Prompetchara E, et al.
Mar Drugs . 2021 Jun; 19(5). PMID: 34063628
It has been recognized that cancer stem-like cells (CSCs) in tumor tissue crucially contribute to therapeutic failure, resulting in a high mortality rate in lung cancer patients. Due to their...
8.
Chemistry of Renieramycins. Part 19: Semi-Syntheses of 22--Amino Ester and Hydroquinone 5--Amino Ester Derivatives of Renieramycin M and Their Cytotoxicity against Non-Small-Cell Lung Cancer Cell Lines
Chamni S, Sirimangkalakitti N, Chanvorachote P, Suwanborirux K, Saito N
Mar Drugs . 2020 Aug; 18(8). PMID: 32785022
Two new series of synthetic renieramycins including 22--amino ester and hydroquinone 5--amino ester derivatives of renieramycin M were semi-synthesized and evaluated for their cytotoxicity against the metastatic non-small-cell lung cancer...
9.
Synergistic Cytotoxicity of Renieramycin M and Doxorubicin in MCF-7 Breast Cancer Cells
Tun J, Salvador-Reyes L, Velarde M, Saito N, Suwanborirux K, Concepcion G
Mar Drugs . 2019 Sep; 17(9). PMID: 31527453
Renieramycin M (RM) is a KCN-stabilized tetrahydroisoquinoline purified from the blue sponge sp., with nanomolar ICs against several cancer cell lines. Our goal is to evaluate its combination effects with...
10.
Jorunnamycin A from sp. Suppresses Epithelial to Mesenchymal Transition and Sensitizes Anoikis in Human Lung Cancer Cells
Ecoy G, Chamni S, Suwanborirux K, Chanvorachote P, Chaotham C
J Nat Prod . 2019 Jul; 82(7):1861-1873. PMID: 31260310
Metastasis is a key driving force behind the high mortality rate associated with lung cancer. Herein, we report the first study revealing the antimetastasis activity of jorunnamycin A, a bistetrahydroisoquinolinequinone...