Supa Hannongbua

Overview

Explore the profile of Supa Hannongbua including associated specialties, affiliations and a list of published articles.

Snapshot

Articles 117

Citations 454

Followers 0

Related Specialties

Chemistry

Biochemistry

Molecular Biology

Top 10 Co-Authors

Patchreenart Saparpakorn

Kiattawee Choowongkomon

Pornpan Pungpo

Auradee Punkvang

M Paul Gleeson

Pharit Kamsri

Peter Wolschann

James Spencer

Songwut Suramitr

Adrian J Mulholland

Published In

J Mol Graph Model

J Mol Model

J Chem Inf Model

Molecules

Chem Biol Interact

Affiliations

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Recent Articles

11.

Structural basis for inhibition of a GH116 β-glucosidase and its missense mutants by GBA2 inhibitors: Crystallographic and quantum chemical study

Meelua W, Thinkumrob N, Saparpakorn P, Pengthaisong S, Hannongbua S, Ketudat Cairns J, et al.

Chem Biol Interact . 2023 Sep; 384:110717. PMID: 37726065

The crystal structure of the Thermoanaerobacterium xylanolyticum in glycoside hydrolase family 116 (TxGH116) β-glucosidase provides a structural model for human GBA2 glucosylceramidase, an enzyme defective in hereditary spastic paraplegia and...

12.

Stability improvement of UV-filter between methoxy cinnamic acid derivatives and cyclodextrins inclusion complexes based on DFT and TD-DFT investigations

Promkatkaew M, Boonsri P, Suramitr S, Karpkird T, Wolschann P, Hannongbua S

J Mol Graph Model . 2023 Sep; 125:108619. PMID: 37666055

Structures and UV-vis absorption spectra of the host-guest interaction of the methoxy cinnamic acid (MCA) derivatives and cyclodextrins (CDs) were performed by using the density functional theory (DFT) and time-dependent...

13.

Bioisosteric Design Identifies Inhibitors of DNA Gyrase ATPase Activity

Kamsri B, Pakamwong B, Thongdee P, Phusi N, Kamsri P, Punkvang A, et al.

J Chem Inf Model . 2023 Apr; 63(9):2707-2718. PMID: 37074047

Mutations in DNA gyrase confer resistance to fluoroquinolones, second-line antibiotics for infections. Identification of new agents that inhibit DNA gyrase ATPase activity is one strategy to overcome this. Here, bioisosteric...

14.

A computational study of the reaction mechanism and stereospecificity of dihydropyrimidinase

Meelua W, Wanjai T, Thinkumrob N, Olah J, Ketudat Cairns J, Hannongbua S, et al.

Phys Chem Chem Phys . 2023 Mar; 25(12):8767-8778. PMID: 36912034

Dihydropyrimidinase (DHPase) is a key enzyme in the pyrimidine pathway, the catabolic route for synthesis of β-amino acids. It catalyses the reversible conversion of 5,6-dihydrouracil (DHU) or 5,6-dihydrothymine (DHT) to...

15.

and studies of potential inhibitors against Dengue viral protein NS5 Methyl Transferase from Ginseng and Notoginseng

Jarerattanachat V, Boonarkart C, Hannongbua S, Auewarakul P, Ardkhean R

J Tradit Complement Med . 2023 Jan; 13(1):1-10. PMID: 36685072

Background And Aim: Dengue is a potentially deadly tropical infectious disease transmitted by mosquito vector with no antiviral drug available to date Dengue NS5 protein is crucial for viral replication...

16.

Insight into free energy and dynamic cross-correlations of residue for binding affinity of antibody and receptor binding domain SARS-CoV-2

Chong W, Saparpakorn P, Sangma C, Lee V, Hannongbua S

Heliyon . 2023 Jan; 9(1):e12667. PMID: 36618128

SARS-CoV-2 virus continues to evolve and mutate causing most of the mutated variants resist to many of the therapeutic monoclonal antibodies (mAbs). Despite several mAbs retained neutralizing capability for Omicron...

17.

Computational design, synthesis and biological evaluation of PDE5 inhibitors based on N,N-diaminoquinazoline and N,N-diaminopurine scaffolds

Somnarin T, Pobsuk N, Chantakul R, Panklai T, Temkitthawon P, Hannongbua S, et al.

Bioorg Med Chem . 2022 Nov; 76:117092. PMID: 36450167

We report the synthesis, and characterization of twenty-nine new inhibitors of PDE5. Structure-based design was employed to modify to our previously reported 2,4-diaminoquinazoline series. Modification include scaffold hopping to 2,6-diaminopurine...

18.

Roles of hybrid donepezil scaffolds as potent human acetylcholinesterase inhibitors using in silico interaction analysis, drug-likeness, and pharmacokinetics prediction

Honorio P, Hannongbua S, Saparpakorn P

Chem Biol Interact . 2022 Oct; 368:110227. PMID: 36302488

Acetylcholinesterase (AChE) is currently one of the potent targets for the treatment of Alzheimer's disease (AD). The discovery of promising new AChE inhibitors using a hybridisation method is considered as...

19.

Risk factors and clinical and laboratory findings associated with feline immunodeficiency virus and feline leukemia virus infections in Bangkok, Thailand

Rungsuriyawiboon O, Jarudecha T, Hannongbua S, Choowongkomon K, Boonkaewwan C, Rattanasrisomporn J

Vet World . 2022 Oct; 15(7):1601-1609. PMID: 36185533

Background And Aim: Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) are retroviruses associated with chronic and neoplastic diseases in domestic and non-domestic cats. There has been increasing interest...

20.

multiscale drug design to discover key structural features of potential JAK2 inhibitors

Kamsri P, Punkvang A, Taveepanich S, Ketrat S, Saparpakorn P, Hannongbua S, et al.

Future Med Chem . 2022 Aug; 14(18):1297-1308. PMID: 36043391

JAK2 inhibitors have been proposed as a new therapeutic option for thalassemia therapy. The objective of this study was to discover the key structural features for improving 2-aminopyrimidine derivatives as...