Sunyoung Chae
Overview
Explore the profile of Sunyoung Chae including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
188
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0
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Recent Articles
1.
Min S, Lee H, Ji J, Heo Y, Kim Y, Chae S, et al.
Nucleic Acids Res
. 2021 Dec;
49(21):12268-12283.
PMID: 34850117
DNA lesions impact on local transcription and the damage-induced transcriptional repression facilitates efficient DNA repair. However, how chromatin dynamics cooperates with these two events remained largely unknown. We here show...
2.
Lee H, Min S, Jung Y, Chae S, Heo J, Lee J, et al.
Nat Commun
. 2021 Oct;
12(1):5931.
PMID: 34635673
The chromatin remodeler RSF1 enriched at mitotic centromeres is essential for proper chromosome alignment and segregation and underlying mechanisms remain to be disclosed. We here show that PLK1 recruitment by...
3.
Kim J, Lee S, Hwang Y, Kim S, Chung J, Park S, et al.
Nucleic Acids Res
. 2021 Oct;
49(19):11083-11102.
PMID: 34614178
Mutual crosstalk among poly(ADP-ribose) (PAR), activated PAR polymerase 1 (PARP1) metabolites, and DNA repair machinery has emerged as a key regulatory mechanism of the DNA damage response (DDR). However, there...
4.
Ji J, Min S, Chae S, Ha G, Kim Y, Park Y, et al.
Nucleic Acids Res
. 2019 May;
47(12):6299-6314.
PMID: 31045206
Histone H2AX undergoes a phosphorylation switch from pTyr142 (H2AX-pY142) to pSer139 (γH2AX) in the DNA damage response (DDR); however, the functional role of H2AX-pY142 remains elusive. Here, we report a...
5.
Ha G, Ji J, Chae S, Park J, Kim S, Lee J, et al.
Nat Commun
. 2019 Apr;
10(1):1577.
PMID: 30952868
DNA double-strand break (DSB) signaling and repair are critical for genome integrity. They rely on highly coordinated processes including posttranslational modifications of proteins. Here we show that Pellino1 (Peli1) is...
6.
Lee H, Lin Z, Chae S, Yoo Y, Kim B, Lee Y, et al.
Nat Commun
. 2018 Sep;
9(1):3848.
PMID: 30242288
Chromatin remodelers regulate the nucleosome barrier during transcription, DNA replication, and DNA repair. The chromatin remodeler RSF1 is enriched at mitotic centromeres, but the functional consequences of this enrichment are...
7.
Lee H, Park Y, Cho M, Chae S, Yoo Y, Kwon M, et al.
Nat Commun
. 2015 Aug;
6:7904.
PMID: 26259146
Accumulation of PLK1 at kinetochores is essential for chromosome alignment and segregation; however, the mechanism underlying PLK1 recruitment to kinetochores remains unresolved. The chromatin remodeller RSF1 tightly associates with centromere...
8.
Min S, Jo S, Lee H, Chae S, Lee J, Ji J, et al.
Cell Cycle
. 2013 Dec;
13(4):666-77.
PMID: 24351651
As a member of imitation switch (ISWI) family in ATP-dependent chromatin remodeling factors, RSF complex consists of SNF2h ATPase and Rsf-1. Although it has been reported that SNF2h ATPase is...
9.
Chae S, Ji J, Kwon S, Lee H, Lim J, Kang D, et al.
Carcinogenesis
. 2013 Mar;
34(7):1680-8.
PMID: 23536579
Hepatitis B virus (HBV) X protein (HBx), encoded by the HBV genome, is involved in the development of HBV-mediated liver cancer, whose frequency is highly correlated with chromosomal instability (CIN)....
10.
Chae S, Kim Y, Lee J, Cho H
Am J Physiol Gastrointest Liver Physiol
. 2012 Feb;
302(9):G1016-24.
PMID: 22323130
Hepatocellular carcinoma (HCC) generally shows chemoresistant features to anticancer agents. Paclitaxel has been clinically used in the treatment of various cancers. However, effect of paclitaxel on HCC has not been...