Sungmi Park
Overview
Explore the profile of Sungmi Park including associated specialties, affiliations and a list of published articles.
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37
Citations
664
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Recent Articles
1.
Ou J, Liu H, Park S, Green M, Zhu L
Front Biosci (Schol Ed)
. 2024 Dec;
16(4):21.
PMID: 39736014
Background: Alternative cleavage and polyadenylation (APA) is a crucial post-transcriptional gene regulation mechanism that regulates gene expression in eukaryotes by increasing the diversity and complexity of both the transcriptome and...
2.
Kim J, Jeon Y, Son J, Pagire H, Pagire S, Ahn J, et al.
Cell Death Dis
. 2024 Aug;
15(8):582.
PMID: 39122684
Age-related macular degeneration (AMD) causes severe blindness in the elderly due to choroidal neovascularization (CNV), which results from the dysfunction of the retinal pigment epithelium (RPE). While normal RPE depends...
3.
Kim B, Lee J, Park S, Suk H
Vision Res
. 2023 May;
209:108247.
PMID: 37156186
This study investigated facial skin color differences before and after makeup. Toward this goal, a photo gauge, devised with a pair of color checkers as a reference, collected face images....
4.
Pagire S, Pagire H, Park K, Bae E, Kim K, Kim M, et al.
Molecules
. 2022 Jun;
27(11).
PMID: 35684355
Serotonin (5-hydroxytryptophan) is a hormone that regulates emotions in the central nervous system. However, serotonin in the peripheral system is associated with obesity and fatty liver disease. Because serotonin cannot...
5.
Kang H, Min B, Choi W, Jeon J, Kim D, Park S, et al.
Exp Mol Med
. 2021 Sep;
53(9):1390-1401.
PMID: 34552205
Obesity is now recognized as a disease. This study revealed a novel role for pyruvate dehydrogenase kinase (PDK) in diet-induced hypertrophic obesity. Mice with global or adipose tissue-specific PDK2 deficiency...
6.
Jin L, Cho M, Kim B, Han J, Park S, Lee I, et al.
BMB Rep
. 2021 Sep;
54(11):563-568.
PMID: 34488935
Cancer cells predominantly generate energy via glycolysis, even in the presence of oxygen, to support abnormal cell proliferation. Suppression of PDHA1 by PDK1 prevents the conversion of cytoplasmic pyruvate into...
7.
Do J, Kim J, Kim M, Lee J, Park S, Yanai R, et al.
Invest Ophthalmol Vis Sci
. 2020 Oct;
61(12):24.
PMID: 33107903
Purpose: To assess the therapeutic effects of fursultiamine on choroidal neovascularization (CNV) through its modulation of inflammation and metabolic reprogramming in the retinal pigment epithelium (RPE). Methods: The anti-angiogenic effects...
8.
Park S, Lee I
J Lipid Atheroscler
. 2020 Aug;
8(1):15-25.
PMID: 32821696
Atherosclerosis is a major cause of morbidity and mortality due to cardiovascular diseases, such as coronary artery disease, stroke, and peripheral vascular disease, that are associated with thrombosis-induced organ infarction....
9.
Min B, Oh C, Park S, Lee J, Go Y, Park B, et al.
Exp Mol Med
. 2019 Oct;
51(10):1-12.
PMID: 31570705
Dyslipidemia-induced atherosclerosis, which has a risk of high morbidity and mortality, can be alleviated by metabolic activation associated with mitochondrial function. The effect of dichloroacetate (DCA), a general pyruvate dehydrogenase...
10.
Cho H, Shin I, Cho K, Yoon H, Yoo E, Kim M, et al.
J Med Chem
. 2019 Aug;
62(18):8461-8479.
PMID: 31469962
Pyruvate dehydrogenase kinases (PDHKs) promote abnormal respiration in cancer cells. Studies with novel resorcinol amide derivatives based on VER-246608 () led to the identification of and containing five-membered heteroaromatic rings...