Sunali Mehta
Overview
Explore the profile of Sunali Mehta including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
429
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0
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Recent Articles
21.
Kazantseva M, Eiholzer R, Mehta S, Taha A, Bowie S, Roth I, et al.
J Pathol
. 2018 Jun;
246(1):77-88.
PMID: 29888503
As tumor protein 53 (p53) isoforms have tumor-promoting, migration, and inflammatory properties, this study investigated whether p53 isoforms contributed to glioblastoma progression. The expression levels of full-length TP53α (TAp53α) and...
22.
Campbell H, Fleming N, Roth I, Mehta S, Wiles A, Williams G, et al.
Nat Commun
. 2018 Jan;
9(1):254.
PMID: 29343721
∆122p53 mice (a model of ∆133p53 isoform) are tumour-prone, have extensive inflammation and elevated serum IL-6. To investigate the role of IL-6 we crossed ∆122p53 mice with IL-6 null mice....
23.
Kazantseva M, Hung N, Mehta S, Roth I, Eiholzer R, Rich A, et al.
Sci Rep
. 2017 May;
7(1):1566.
PMID: 28484276
Accumulating evidence suggests tumor protein 53 (p53) promotes correct cellular differentiation. Thus, mutant TP53 may be more frequent in tumors with irregular differentiation. This study investigated whether TP53 mutations were...
24.
Nasef N, Mehta S, Ferguson L
Arch Toxicol
. 2017 Jan;
91(3):1131-1141.
PMID: 28130581
Chronic inflammation is defined by the persistence of inflammatory processes beyond their physiological function, resulting in tissue destruction. Chronic inflammation is implicated in the progression of many chronic diseases and...
25.
Mehta S, Tsai P, Lasham A, Campbell H, Reddel R, Braithwaite A, et al.
Cancer Res
. 2016 Dec;
76(24):7151-7159.
PMID: 27913434
TP53 undergoes multiple RNA-splicing events, resulting in at least nine mRNA transcripts encoding at least 12 functionally different protein isoforms. Antibodies specific to p53 protein isoforms have proven difficult to...
26.
Nasef N, Mehta S, Powell P, Marlow G, Wileman T, Ferguson L
PLoS One
. 2015 Jun;
10(6):e0130910.
PMID: 26110654
Background: Inflammatory bowel disease (IBD) is a heterogeneous chronic inflammatory disease affecting the gut with limited treatment success for its sufferers. This suggests the need for better understanding of the...
27.
Nasef N, Mehta S, Murray P, Marlow G, Ferguson L
Nutrients
. 2014 Nov;
6(11):5265-79.
PMID: 25415606
Pattern recognition receptors such as Toll-Like Receptor 2 (TLR2) and 4 (TLR4) are important in detecting and responding to stress and bacterial stimuli. Defect or damage in the TLR2 and...
28.
Nasef N, Mehta S, Ferguson L
Front Genet
. 2014 Apr;
5:64.
PMID: 24772116
There are millions of microbes that live in the human gut. These are important in digestion as well as defense. The host immune system needs to be able to distinguish...
29.
Mehta S, Shelling A, Muthukaruppan A, Lasham A, Blenkiron C, Laking G, et al.
Ther Adv Med Oncol
. 2011 Jul;
2(2):125-48.
PMID: 21789130
Over the last 10 years there has been an explosion of information about the molecular biology of cancer. A challenge in oncology is to translate this information into advances in...