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» Authors » Sunali Goonesekera

Sunali Goonesekera

Explore the profile of Sunali Goonesekera including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 243
Followers 0
Related Specialties
Public Health
Science
Biochemistry
Top 10 Co-Authors
Barry R Bloom
Csaba Szabo
Jerry Sadoff
Willem Andreas Germishuizen
Yun-Ling Wong
David Edwards
Garry J Southan
Susan Shetterly
Katharina Elbert
P Bernard Fourie
Published In
Proc Natl Acad Sci U S A
J Biol Chem
Trop Med Int Health
Mutat Res
Pharmacoepidemiol Drug Saf
Affiliations
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Recent Articles
1.
The burden of heart failure in North America and Western Europe
Goonesekera S, Rudnicka-Noulin D, Isherwood A
Future Cardiol . 2020 Oct; 17(4):637-646. PMID: 33095033
We depict the burden of heart failure (HF) in North America (NA) and Western Europe (WE), using a cyclical flow diagram of patients from diagnosis/hospitalization until treatment, stabilization and decompensation/death. ...
2.
Evaluation of propensity scores, disease risk scores, and regression in confounder adjustment for the safety of emerging treatment with group sequential monitoring
Xu S, Shetterly S, Cook A, Raebel M, Goonesekera S, Shoaibi A, et al.
Pharmacoepidemiol Drug Saf . 2016 Feb; 25(4):453-61. PMID: 26875591
Purpose: The objective of this study was to evaluate regression, matching, and stratification on propensity score (PS) or disease risk score (DRS) in a setting of sequential analyses where statistical...
3.
Bi-directional screening for tuberculosis and diabetes: a systematic review
Jeon C, Harries A, Baker M, Hart J, Kapur A, Lonnroth K, et al.
Trop Med Int Health . 2010 Oct; 15(11):1300-14. PMID: 20958887
Objective: To assess the yield of finding additional TB or diabetes mellitus (DM) cases through systematic screening and to determine the effectiveness of preventive TB therapy in people with DM....
4.
Immunization by a bacterial aerosol
Garcia-Contreras L, Wong Y, Muttil P, Padilla D, Sadoff J, Derousse J, et al.
Proc Natl Acad Sci U S A . 2008 Mar; 105(12):4656-60. PMID: 18344320
By manufacturing a single-particle system in two particulate forms (i.e., micrometer size and nanometer size), we have designed a bacterial vaccine form that exhibits improved efficacy of immunization. Microstructural properties...
5.
Drying a tuberculosis vaccine without freezing
Wong Y, Sampson S, Germishuizen W, Goonesekera S, Caponetti G, Sadoff J, et al.
Proc Natl Acad Sci U S A . 2007 Feb; 104(8):2591-5. PMID: 17299039
With the increasing incidence of tuberculosis and drug resistant disease in developing countries due to HIV/AIDS, there is a need for vaccines that are more effective than the present bacillus...
6.
Suppression of intestinal polyposis in Apcmin/+ mice by targeting the nitric oxide or poly(ADP-ribose) pathways
Mabley J, Pacher P, Bai P, Wallace R, Goonesekera S, Virag L, et al.
Mutat Res . 2004 Apr; 548(1-2):107-16. PMID: 15063141
Min mice have a germ-line nonsense mutation at codon 850 of the adenomatous polyposis coli (Apc) gene. These mice spontaneously develop multiple polyps in the small and large intestine at...
7.
Identification of conserved domains in Salmonella muenchen flagellin that are essential for its ability to activate TLR5 and to induce an inflammatory response in vitro
Murthy K, Deb A, Goonesekera S, Szabo C, Salzman A
J Biol Chem . 2003 Nov; 279(7):5667-75. PMID: 14634022
The bacterial surface protein flagellin is widely distributed and well conserved among distant bacterial species. We and other investigators have reported recently that purified flagellin from Salmonella dublin or recombinant...