Sukhada Bhave
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Explore the profile of Sukhada Bhave including associated specialties, affiliations and a list of published articles.
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21
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303
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Recent Articles
1.
Snyder J, Ahmed M, Bhave S, Hotta R, Koppes R, Goldstein A, et al.
Adv Biol (Weinh)
. 2024 Dec;
:e2300566.
PMID: 39703141
Neurosensory circuits of the gastrointestinal tract sense microbial and nutrient changes in the gut; however, studying these circuits in vivo is hindered by invasive techniques and ethical concerns. Here, an...
2.
Rahman A, Ohkura T, Bhave S, Pan W, Ohishi K, Ott L, et al.
JCI Insight
. 2024 Jul;
9(17).
PMID: 39042470
The goal of this study was to determine if transplantation of enteric neural stem cells (ENSCs) can rescue the enteric nervous system, restore gut motility, reduce colonic inflammation, and improve...
3.
Mueller J, Stavely R, Guyer R, Soos A, Bhave S, Han C, et al.
Stem Cells Transl Med
. 2024 Feb;
13(5):490-504.
PMID: 38387006
Regenerative cell therapy to replenish the missing neurons and glia in the aganglionic segment of Hirschsprung disease represents a promising treatment option. However, the success of cell therapies for this...
4.
Hotta R, Pan W, Bhave S, Nagy N, Stavely R, Ohkura T, et al.
Cell Transplant
. 2023 Dec;
32:9636897231215233.
PMID: 38049927
The enteric nervous system (ENS) is an extensive network of neurons and glia within the wall of the gastrointestinal (GI) tract that regulates many essential GI functions. Consequently, disorders of...
5.
Hotta R, Rahman A, Bhave S, Stavely R, Pan W, Srinivasan S, et al.
Stem Cell Res Ther
. 2023 Sep;
14(1):232.
PMID: 37667277
Background: Enteric neuropathies, which result from abnormalities of the enteric nervous system, are associated with significant morbidity and high health-care costs, but current treatments are unsatisfactory. Cell-based therapy offers an...
6.
Guyer R, Stavely R, Robertson K, Bhave S, Mueller J, Picard N, et al.
Cell Rep
. 2023 Mar;
42(3):112194.
PMID: 36857184
The enteric nervous system (ENS) consists of glial cells (EGCs) and neurons derived from neural crest precursors. EGCs retain capacity for large-scale neurogenesis in culture, and in vivo lineage tracing...
7.
Pan W, Rahman A, Stavely R, Bhave S, Guyer R, Omer M, et al.
Stem Cells Transl Med
. 2022 Nov;
11(12):1232-1244.
PMID: 36322091
Cell therapy offers the potential to replace the missing enteric nervous system (ENS) in patients with Hirschsprung disease (HSCR) and to restore gut function. The Schwann cell (SC) lineage has...
8.
Bhave S, Guyer R, Picard N, Omer M, Hotta R, Goldstein A
Front Cell Dev Biol
. 2022 Aug;
10:917243.
PMID: 35959491
Hirschsprung disease is most often characterized by aganglionosis limited to the distal colon and rectum, and mice lacking the Endothelin receptor type B (Ednrb) faithfully recapitulate this phenotype. However, despite...
9.
Stavely R, Hotta R, Picard N, Rahman A, Pan W, Bhave S, et al.
Sci Transl Med
. 2022 May;
14(646):eabl8753.
PMID: 35613280
Stem cell therapies for nervous system disorders are hindered by a lack of accessible autologous sources of neural stem cells (NSCs). In this study, neural crest-derived Schwann cells are found...
10.
Bhave S, Ho W, Cheng K, Omer M, Bousquet N, Guyer R, et al.
Neurogastroenterol Motil
. 2022 Mar;
34(5):e14357.
PMID: 35279902
Background: Tamoxifen is widely used for Cre-estrogen receptor-mediated genomic recombination in transgenic mouse models to mark cells for lineage tracing and to study gene function. However, recent studies have highlighted...