Sujata Prasad
Overview
Explore the profile of Sujata Prasad including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
244
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Recent Articles
1.
Prasad S, Singh S, Menge S, Mohapatra I, Kim S, Helland L, et al.
Front Immunol
. 2024 Sep;
15:1387903.
PMID: 39234241
The gastrointestinal (GI) tract redox environment, influenced by commensal microbiota and bacterial-derived metabolites, is crucial in shaping T-cell responses. Specifically, metabolites from gut microbiota (GM) exhibit robust anti-inflammatory effects, fostering...
2.
Singh S, Barik D, Arukha A, Prasad S, Mohapatra I, Singh A, et al.
Biomedicines
. 2023 Oct;
11(10).
PMID: 37892995
Conventional and cancer immunotherapies encompass diverse strategies to address various cancer types and stages. However, combining these approaches often encounters limitations such as non-specific targeting, resistance development, and high toxicity,...
3.
Singh S, Barik D, Lawrie K, Mohapatra I, Prasad S, Naqvi A, et al.
Int J Mol Sci
. 2023 Oct;
24(19).
PMID: 37834408
The mTOR signaling pathway plays a pivotal and intricate role in the pathogenesis of glioblastoma, driving tumorigenesis and proliferation. Mutations or deletions in the PTEN gene constitutively activate the mTOR...
4.
Prasad S, Singh A, Hu S, Sheng W, Chauhan P, Lokensgard J
iScience
. 2023 May;
26(5):106628.
PMID: 37192971
This study was undertaken to investigate the role of CD4+FoxP3+ regulatory T cells (Tregs) in regulating neuroinflammation during viral Ag-challenge and re-challenge. CD8 lymphocytes persisting within tissues are designated tissue-resident...
5.
Chauhan P, Sheng W, Hu S, Prasad S, Lokensgard J
Brain Sci
. 2021 Nov;
11(11).
PMID: 34827481
The role of select pro- and anti-inflammatory mediators in driving microglial cell polarization into classically (M1), or alternatively, (M2) activated states, as well as the subsequent differential responses of these...
6.
Prasad S, Sheng W, Hu S, Chauhan P, Lokensgard J
Front Cell Neurosci
. 2021 Aug;
15:686340.
PMID: 34447297
Upon reactivation of quiescent neurotropic viruses antigen (Ag)-specific brain resident-memory CD8+ T-cells (bT) may respond to -produced viral Ag through the rapid release of IFN-γ, which drives subsequent interferon-stimulated gene...
7.
Chauhan P, Hu S, Prasad S, Sheng W, Lokensgard J
Glia
. 2020 Oct;
69(4):858-871.
PMID: 33128485
Microglial cells are the main reservoir for HIV-1 within the brain and potential exists for negative immune checkpoint blockade therapies to purge this viral reservoir. Here, we investigated cytolytic responses...
8.
Prasad S, Hu S, Sheng W, Chauhan P, Lokensgard J
iScience
. 2019 Oct;
20:512-526.
PMID: 31655062
HIV-associated neurocognitive disorders (HAND) persist even during effective combination antiretroviral therapy (cART). Although the cause of HAND is unknown, studies link chronic immune activation, neuroinflammation, and cerebrospinal fluid viral escape...
9.
Sheng W, Chauhan P, Hu S, Prasad S, Lokensgard J
Pain Res Manag
. 2019 Jul;
2019:1260353.
PMID: 31354896
The most common neurological complication in patients receiving successful combination antiretroviral therapy (cART) is peripheral neuropathic pain. Data show that distal symmetric polyneuropathy (DSP) also develops along with murine acquired...
10.