Sujata Jana
Overview
Explore the profile of Sujata Jana including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
155
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0
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Recent Articles
1.
Li S, Wong A, Sun H, Bhatia V, Javier G, Jana S, et al.
Nat Genet
. 2024 Feb;
56(3):371-376.
PMID: 38424461
Available genetically defined cancer models are limited in genotypic and phenotypic complexity and underrepresent the heterogeneity of human cancer. Here, we describe a combinatorial genetic strategy applied to an organoid...
2.
Li S, Wong A, Sun H, Bhatia V, Javier G, Jana S, et al.
bioRxiv
. 2023 Aug;
PMID: 37609344
Available genetically-defined cancer models are limited in genotypic and phenotypic complexity and underrepresent the heterogeneity of human cancer. Herein, we describe a combinatorial genetic strategy applied to an organoid transformation...
3.
Jana S, Brahma S, Arora S, Wladyka C, Hoang P, Blinka S, et al.
Cancer Cell
. 2023 Apr;
41(5):853-870.e13.
PMID: 37084735
We uncover a tumor-suppressive process in urothelium called transcriptional-translational conflict caused by deregulation of the central chromatin remodeling component ARID1A. Loss of Arid1a triggers an increase in a nexus of...
4.
Jana S, Deo R, Hough R, Liu Y, Horn J, Wright J, et al.
JCI Insight
. 2021 May;
6(11).
PMID: 34032633
Using genetically engineered mouse models, this work demonstrates that protein synthesis is essential for efficient urothelial cancer formation and growth but dispensable for bladder homeostasis. Through a candidate gene analysis...
5.
Liu Y, Horn J, Banda K, Goodman A, Lim Y, Jana S, et al.
Sci Transl Med
. 2019 Aug;
11(503).
PMID: 31366581
The androgen receptor (AR) is a driver of cellular differentiation and prostate cancer development. An extensive body of work has linked these normal and aberrant cellular processes to mRNA transcription;...
6.
Winters B, De Sarkar N, Arora S, Bolouri H, Jana S, Vakar-Lopez F, et al.
JCI Insight
. 2019 May;
5.
PMID: 31145100
Background: Little is known about the genomic differences between metastatic urothelial carcinoma (LTUC) and upper tract urothelial carcinoma (UTUC). We compare genomic features of primary and metastatic UTUC and LTUC...
7.
Jana S, Hsieh A, Gupta R
Cell Death Dis
. 2017 Oct;
8(10):e3093.
PMID: 28981101
Pus10 is a pseudouridine synthase present in Archaea and Eukarya, but not in Bacteria and yeast. It has been suggested that the human PUS10 (DOBI) gene is needed during TRAIL-induced...
8.
Joardar A, Jana S, Fitzek E, Gurha P, Majumder M, Chatterjee K, et al.
RNA
. 2013 Jul;
19(9):1279-94.
PMID: 23898217
Pseudouridines (Ψ) are found in structurally and functionally important regions of RNAs. Six families of Ψ synthases, TruA, TruB, TruD, RsuA, RluA, and Pus10 have been identified. Pus10 is present...
9.
Bose Jr K, Jana S, Bisai S, Mukhopadhyay A, Bhadra M
Malays J Nutr
. 2012 Jun;
13(2):131-9.
PMID: 22691751
The nutritional status of tuberculosis patients (TBP) and controls (CT) was compared among adult (> 20 years) Bengalees in Shyamnagar, Barrackpore, Naihati and Jagaddal of North 24 Parganas District, West...
10.
Blaby I, Majumder M, Chatterjee K, Jana S, Grosjean H, de Crecy-Lagard V, et al.
RNA
. 2011 Jun;
17(7):1367-80.
PMID: 21628430
Pseudouridine (Ψ), the isomer of uridine, is commonly found at various positions of noncoding RNAs of all organisms. Ψ residues are formed by a number of single- or multisite specific...