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Subramaniam Jayanthi

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Citations 1804
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Recent Articles
1.
Munoz C, Jayanthi S, Ladenheim B, Cadet J
Front Mol Neurosci . 2023 Jan; 15:1104657. PMID: 36710935
Methamphetamine (METH) is a popular but harmful psychostimulant. METH use disorder (MUD) is characterized by compulsive and continued use despite adverse life consequences. METH users experience impairments in learning and...
2.
Garrett T, Tulloch I, McCoy M, Ladenheim B, Jayanthi S, Krasnova I, et al.
J Drug Alcohol Res . 2022 Sep; 1(1). PMID: 36147517
The present study investigated whether chronic methamphetamine (METH) would suppress METH-induced mRNA expression of immediate early genes (IEGs) in the rat brain. Rats were given METH or saline over two...
3.
Jayanthi S, Ladenheim B, Sullivan P, McCoy M, Krasnova I, Goldstein D, et al.
Int J Mol Sci . 2022 Sep; 23(17). PMID: 36077488
Perturbations in striatal dopamine (DA) homeostasis might underlie the behavioral and pathobiological consequences of METH use disorder in humans. To identify potential consequences of long-term METH exposure, we modeled the...
4.
Daiwile A, Sullivan P, Jayanthi S, Goldstein D, Cadet J
Int J Mol Sci . 2022 Apr; 23(8). PMID: 35457170
Methamphetamine (METH) use disorder affects both sexes, with sex differences occurring in behavioral, structural, and biochemical consequences. The molecular mechanisms underlying these differences are unclear. Herein, we used a rat...
5.
Daiwile A, Jayanthi S, Cadet J
Neurosci Biobehav Rev . 2022 Apr; 137:104674. PMID: 35452744
Methamphetamine (METH) use, and misuse are associated with severe socioeconomic consequences. METH users develop tolerance, lose control over drug taking behaviors, and suffer frequent relapses even during treatment. The clinical...
6.
Jayanthi S, Peesapati R, McCoy M, Ladenheim B, Cadet J
Mol Neurobiol . 2022 Jan; 59(2):1238-1248. PMID: 34978045
Methamphetamine (METH) use disorder (MUD) is characterized by compulsive and repeated drug taking despite negative life consequences. Large intake of METH in humans and animals is accompanied by dysfunctions in...
7.
Jayanthi S, McCoy M, Cadet J
Genes (Basel) . 2021 Oct; 12(10). PMID: 34681009
Methamphetamine (METH)-use disorder (MUD) is a very serious, potentially lethal, biopsychosocial disease. Exposure to METH causes long-term changes to brain regions involved in reward processing and motivation, leading vulnerable individuals...
8.
Jayanthi S, Daiwile A, Cadet J
Exp Neurol . 2021 Jun; 344:113795. PMID: 34186102
Methamphetamine (METH) is an illicit psychostimulant that is abused throughout the world. METH addiction is also a major public health concern and the abuse of large doses of the drug...
9.
Cadet J, Jayanthi S
Curr Neuropharmacol . 2021 May; 19(12):2060-2066. PMID: 34030618
The persistence of the addiction phenotype in methamphetamine use disorder (MUD) suggests the potential presence of epigenetic changes and potential structural adaptations that may drive the manifestations of MUD in...
10.
Cadet J, Jayanthi S
Neurochem Int . 2021 May; 147:105069. PMID: 33992741
Substance use disorders are complex biopsychosocial disorders that have substantial negative neurocognitive impact in various patient populations. These diseases involve the compulsive use of licit or illicit substances despite adverse...