Alpha 2.0
Login Register
» Authors » Stuart Meier

Stuart Meier

Explore the profile of Stuart Meier including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 24
Citations 861
Followers 0
Related Specialties
Biology
General Medicine
Science
Top 10 Co-Authors
Chris Gehring
Lara Donaldson
Keertan Dheda
Suzette Oelofse
Aliasgar Esmail
Anil Pooran
Luisa Ederli
Stefania Pasqualini
Gerard Tromp
Lusisizwe Kwezi
Published In
PLoS One
Plant Signal Behav
Methods Mol Biol
Am J Respir Crit Care Med
New Phytol
Affiliations
Soon will be listed here.
Recent Articles
1.
SARS-CoV-2 Viral Replication Persists in the Human Lung for Several Weeks after Symptom Onset
Tomasicchio M, Jaumdally S, Wilson L, Kotze A, Semple L, Meier S, et al.
Am J Respir Crit Care Med . 2024 Jan; 209(7):840-851. PMID: 38226855
In the upper respiratory tract, replicating (culturable) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is recoverable for ∼4-8 days after symptom onset, but there is a paucity of data about...
2.
RNA-seq analysis of gene expression profiles in posttraumatic stress disorder, Parkinson's disease and schizophrenia identifies roles for common and distinct biological pathways
Hemmings S, Swart P, Womersely J, Ovenden E, van den Heuvel L, McGregor N, et al.
Discov Ment Health . 2023 Oct; 2(1):6. PMID: 37861850
Evidence suggests that shared pathophysiological mechanisms in neuropsychiatric disorders (NPDs) may contribute to risk and resilience. We used single-gene and network-level transcriptomic approaches to investigate shared and disorder-specific processes underlying...
3.
Proteomic Profiling of Urine From Hospitalized Patients With Severe Pneumonia due to SARS-CoV-2 vs Other Causes: A Preliminary Report
Wilson L, Chang J, Meier S, Ganief T, Ganief N, Oelofse S, et al.
Open Forum Infect Dis . 2023 Oct; 10(10):ofad451. PMID: 37799131
The pathogenesis of coronavirus disease 2019 (COVID-19) pneumonia remains poorly understood. The urine proteome of hospitalized patients with severe COVID-19 pneumonia, compared with severe non-COVID-19 pneumonia controls, was distinct and...
4.
Comparison of two diagnostic intervention packages for community-based active case finding for tuberculosis: an open-label randomized controlled trial
Esmail A, Randall P, Oelofse S, Tomasicchio M, Pooran A, Meldau R, et al.
Nat Med . 2023 Mar; 29(4):1009-1016. PMID: 36894651
Two in every five patients with active tuberculosis (TB) remain undiagnosed or unreported. Therefore community-based, active case-finding strategies require urgent implementation. However, whether point-of-care (POC), portable battery-operated, molecular diagnostic tools...
5.
Neutrophil degranulation, NETosis and platelet degranulation pathway genes are co-induced in whole blood up to six months before tuberculosis diagnosis
Meier S, Seddon J, Maasdorp E, Kleynhans L, Plessis N, Loxton A, et al.
PLoS One . 2022 Dec; 17(12):e0278295. PMID: 36454773
Mycobacterium tuberculosis (M.tb) causes tuberculosis (TB) and remains one of the leading causes of mortality due to an infectious pathogen. Host immune responses have been implicated in driving the progression...
6.
Salt-Specific Gene Expression Reveals Elevated Auxin Levels in Plants Grown Under Saline Conditions
Cackett L, Cannistraci C, Meier S, Ferrandi P, Pencik A, Gehring C, et al.
Front Plant Sci . 2022 Feb; 13:804716. PMID: 35222469
Soil salinization is increasing globally, driving a reduction in crop yields that threatens food security. Salinity stress reduces plant growth by exerting two stresses on plants: rapid shoot ion-independent effects...
7.
An All-Oral 6-Month Regimen for Multidrug-Resistant Tuberculosis: A Multicenter, Randomized Controlled Clinical Trial (the NExT Study)
Esmail A, Oelofse S, Lombard C, Perumal R, Mbuthini L, Goolam Mahomed A, et al.
Am J Respir Crit Care Med . 2022 Feb; 205(10):1214-1227. PMID: 35175905
Improving treatment outcomes while reducing drug toxicity and shortening the treatment duration to ∼6 months remains an aspirational goal for the treatment of multidrug-resistant/rifampicin-resistant tuberculosis (MDR/RR-TB). To conduct a multicenter...
8.
The Peripheral Blood Transcriptome Is Correlated With PET Measures of Lung Inflammation During Successful Tuberculosis Treatment
Odia T, Malherbe S, Meier S, Maasdorp E, Kleynhans L, Plessis N, et al.
Front Immunol . 2021 Mar; 11:596173. PMID: 33643286
Pulmonary tuberculosis (PTB) is characterized by lung granulomas, inflammation and tissue destruction. Here we used within-subject peripheral blood gene expression over time to correlate with the within-subject lung metabolic activity,...
9.
The utility of high-flow nasal oxygen for severe COVID-19 pneumonia in a resource-constrained setting: A multi-centre prospective observational study
Calligaro G, Lalla U, Audley G, Gina P, Miller M, Mendelson M, et al.
EClinicalMedicine . 2020 Oct; 28:100570. PMID: 33043285
Background: The utility of heated and humidified high-flow nasal oxygen (HFNO) for severe COVID-19-related hypoxaemic respiratory failure (HRF), particularly in settings with limited access to intensive care unit (ICU) resources,...
10.
The arabidopsis cyclic nucleotide interactome
Donaldson L, Meier S, Gehring C
Cell Commun Signal . 2016 May; 14(1):10. PMID: 27170143
Background: Cyclic nucleotides have been shown to play important signaling roles in many physiological processes in plants including photosynthesis and defence. Despite this, little is known about cyclic nucleotide-dependent signaling...