Stuart L Graham
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Explore the profile of Stuart L Graham including associated specialties, affiliations and a list of published articles.
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188
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2982
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Recent Articles
1.
Basavarajappa D, Chitranshi N, Oddin Mirshahvaladi S, Gupta V, Palanivel V, Parrilla G, et al.
FASEB J
. 2025 Mar;
39(6):e70465.
PMID: 40079201
Glaucoma, a leading cause of irreversible blindness, is characterized by the progressive loss of retinal ganglion cells (RGCs) and optic nerve damage, often associated with elevated intraocular pressure (IOP). Retinoid...
2.
Kolovos A, Qassim A, Hassall M, Marshall H, Schmidt J, Nguyen T, et al.
Ophthalmology
. 2025 Feb;
PMID: 40010646
Objective: Pseudoexfoliation syndrome (PEX) is a known risk factor for glaucoma, but its individual clinical course ranges from no glaucoma to total blindness. This study investigated whether polygenic risk scores...
3.
Shen T, Sheriff S, Qu Y, Gupta V, Graham S, Klistorner A, et al.
Brain Imaging Behav
. 2025 Jan;
PMID: 39871045
Magnetic resonance imaging (MRI) is frequently used to monitor disease progression in multiple sclerosis (MS). This study aims to systematically evaluate the correlation between MRI measures and histopathological changes, including...
4.
Parrilla G, Salkar A, Vander Wall R, Gupta V, Graham S, You Y
Aging Dis
. 2024 Sep;
PMID: 39226160
Glaucoma is a neurodegenerative disease affecting millions worldwide, characterised by retinal ganglion cell (RGC) degeneration which leads to blindness in more advanced cases. Although the pathogenesis and underlying mechanisms of...
5.
Parrilla G, Salkar A, Vander Wall R, Gupta V, Graham S, You Y
Aging Dis
. 2024 Aug;
15(5):2301-2314.
PMID: 39191397
Glaucoma is a neurodegenerative disease affecting millions worldwide, characterised by retinal ganglion cell (RGC) degeneration which leads to blindness in more advanced cases. Although the pathogenesis and underlying mechanisms of...
6.
Parrilla G, Vander Wall R, Chitranshi N, Basavarajappa D, Gupta V, Graham S, et al.
Neuroscience
. 2024 Aug;
559:91-104.
PMID: 39173871
Neurodegenerative and demyelinating disease, such as multiple sclerosis (MS) are at the forefront of medical research and the discovery of new drugs and therapeutics. One phenomenon of degeneration seen in...
7.
Palanivel V, Gupta V, Chitranshi N, Tietz O, Vander Wall R, Blades R, et al.
PNAS Nexus
. 2024 Aug;
3(8):pgae299.
PMID: 39114576
Neuropeptide Y (NPY), an endogenous peptide composed of 36 amino acids, has been investigated as a potential therapeutic agent for neurodegenerative diseases due to its neuroprotective attributes. This study investigated...
8.
Shen T, Sheriff S, You Y, Jiang J, Schulz A, Francis H, et al.
Aging Dis
. 2024 Jun;
15(5):2315-2327.
PMID: 38916728
Aging is associated with progressive brain atrophy and declines in learning and memory, often attributed to hippocampal or cortical deterioration. The role of brain-derived neurotrophic factor (BDNF) in modulating the...
9.
Maha Thananthirige K, Chitranshi N, Basavarajappa D, Rajput R, Abbasi M, Palanivel V, et al.
Acta Neuropathol Commun
. 2024 Jun;
12(1):89.
PMID: 38845058
The microtubule-associated protein Tau is a key player in various neurodegenerative conditions, including Alzheimer's disease (AD) and Tauopathies, where its hyperphosphorylation disrupts neuronal microtubular lattice stability. Glaucoma, a neurodegenerative disorder...
10.
Gaire B, Koronyo Y, Fuchs D, Shi H, Rentsendorj A, Danziger R, et al.
Prog Retin Eye Res
. 2024 May;
101:101273.
PMID: 38759947
The retina is an emerging CNS target for potential noninvasive diagnosis and tracking of Alzheimer's disease (AD). Studies have identified the pathological hallmarks of AD, including amyloid β-protein (Aβ) deposits...