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Jamie E Craig

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Articles 334
Citations 8047
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Recent Articles
1.
Kolovos A, Qassim A, Hassall M, Marshall H, Schmidt J, Nguyen T, et al.
Ophthalmology . 2025 Feb; PMID: 40010646
Objective: Pseudoexfoliation syndrome (PEX) is a known risk factor for glaucoma, but its individual clinical course ranges from no glaucoma to total blindness. This study investigated whether polygenic risk scores...
2.
Kolovos A, Maxwell G, Souzeau E, Craig J
Clin Exp Ophthalmol . 2025 Feb; PMID: 39929609
Precision medicine is paving the way for personalised risk assessment, and its translation into glaucoma clinics holds potential to change current management paradigms. Our understanding of glaucoma's genetic architecture has...
3.
Hollitt G, Hassall M, Siggs O, Craig J, Souzeau E
BMC Med Genomics . 2025 Jan; 18(1):21. PMID: 39885483
Background: Polygenic risk scores (PRS), which provide an individual probabilistic estimate of genetic susceptibility to develop a disease, have shown effective risk stratification for glaucoma onset. However, there is limited...
4.
Maxwell G, Allen R, Kelley S, Hodge L, Hollitt G, Seviiri M, et al.
PLoS One . 2024 Dec; 19(12):e0312390. PMID: 39724070
Glaucoma is the leading cause of irreversible blindness with early detection and intervention critical to slowing disease progression. However, half of those affected are undiagnosed. This is largely due to...
5.
He W, Lee S, Torres S, Han X, Gharahkhani P, Hunter M, et al.
JAMA Ophthalmol . 2024 Nov; 143(1):15-22. PMID: 39570582
Importance: Early detection of glaucoma is essential to timely monitoring and treatment, and primary open-angle glaucoma risk can be assessed by measuring intraocular pressure (IOP) or optic nerve head vertical...
6.
Diaz-Torres S, He W, Yu R, Khawaja A, Hammond C, Hysi P, et al.
Nat Commun . 2024 Nov; 15(1):9959. PMID: 39551815
Primary open-angle glaucoma typically presents as two subtypes. This study aimed to elucidate the shared and distinct genetic architectures of normal-tension (NTG) and high-tension glaucoma (HTG), motivated by the need...
7.
Chaurasia A, Liu G, Greatbatch C, Gharahkhani P, Craig J, Mackey D, et al.
Eye (Lond) . 2024 Nov; 39(1):109-117. PMID: 39501004
Importance: Worldwide, glaucoma is a leading cause of irreversible blindness. Timely detection is paramount yet challenging, particularly in resource-limited settings. A novel, computer vision-based model for glaucoma screening using fundus...
8.
Hollitt G, Keane M, Nguyen T, Hassall M, Siggs O, Craig J, et al.
Clin Exp Ophthalmol . 2024 Sep; 52(9):957-972. PMID: 39245560
Background: Effective clinical implementation of polygenic risk testing for glaucoma relies on healthcare professionals' attitudes and knowledge of the test. Given the emerging applications of the test, it will likely...
9.
Estevez J, Liu E, Patel C, Roulston T, Howard N, Lake S, et al.
Prim Care Diabetes . 2024 Sep; 18(5):547-554. PMID: 39232978
Aims: Diabetic nephropathy, vision loss and diabetic retinopathy (DR) are frequent comorbidities among individuals with type 2 diabetes (T2D). The Retinopathy in People Currently On Renal Dialysis (RiPCORD) study sought...
10.
Chaurasia A, Greatbatch C, Han X, Gharahkhani P, Mackey D, Macgregor S, et al.
Ophthalmol Sci . 2024 Jul; 4(5):100540. PMID: 39051045
Objective: An enlarged cup-to-disc ratio (CDR) is a hallmark of glaucomatous optic neuropathy. Manual assessment of the CDR may be less accurate and more time-consuming than automated methods. Here, we...