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Stuart G Jarrett

Explore the profile of Stuart G Jarrett including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 1315
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Recent Articles
1.
Jarrett S, Wolf Horrell E, Christian P, Vanover J, Boulanger M, Zou Y, et al.
Mol Cell . 2022 Nov; 82(22):4400. PMID: 36400011
No abstract available.
2.
Jarrett S, Carter K, Bautista R, He D, Wang C, DOrazio J
J Biol Chem . 2021 Jul; 296:100185. PMID: 34237903
No abstract available.
3.
Jarrett S, Carter K, Shelton B, DOrazio J
Sci Rep . 2021 Jan; 11(1):847. PMID: 33414513
No abstract available.
4.
Jarrett S, Wolf Horrell E, DOrazio J
Nucleic Acids Res . 2020 Oct; 48(20):11814. PMID: 33091128
No abstract available.
5.
Chaiprasongsuk A, Janjetovic Z, Kim T, Jarrett S, DOrazio J, Holick M, et al.
Redox Biol . 2019 May; 24:101206. PMID: 31039479
We tested whether novel CYP11A1-derived vitamin D- and lumisterol-hydroxyderivatives, including 1,25(OH)D, 20(OH)D, 1,20(OH)D, 20,23(OH)D, 1,20,23(OH)D, lumisterol, 20(OH)L, 22(OH)L, 20,22(OH)L, and 24(OH)L, can protect against UVB-induced damage in human epidermal keratinocytes....
6.
Holcomb N, Bautista R, Jarrett S, Carter K, Gober M, DOrazio J
Adv Protein Chem Struct Biol . 2019 Feb; 115:247-295. PMID: 30798934
Malignant melanoma of the skin is the leading cause of death from skin cancer and ranks fifth in cancer incidence among all cancers in the United States. While melanoma mortality...
7.
Jarrett S, Carter K, Bautista R, He D, Wang C, DOrazio J
J Biol Chem . 2018 Oct; 293(49):19025-19037. PMID: 30327428
Blunted melanocortin 1 receptor (MC1R) signaling promotes melanocyte genomic instability in part by attenuating cAMP-mediated DNA repair responses, particularly nucleotide excision repair (NER), which recognizes and clears mutagenic photodamage. cAMP-enhanced...
8.
Jarrett S, Carter K, Shelton B, DOrazio J
Sci Rep . 2017 Sep; 7(1):11708. PMID: 28916831
Using primary melanocytes and HEK293 cells, we found that cAMP signaling accelerates repair of bi- and mono-functional platinum-induced DNA damage. Elevating cAMP signaling either by the agonistic MC1R ligand melanocyte...
9.
Janjetovic Z, Jarrett S, Lee E, Duprey C, Reiter R, Slominski A
Sci Rep . 2017 Apr; 7(1):1274. PMID: 28455491
Ultraviolet light (UV) is an inducer of reactive oxygen species (ROS) as well as 6-4-photoproducts and cyclobutane pyrimidine dimers (CPD) in the skin, which further cause damage to the skin...
10.
Wolf Horrell E, Jarrett S, Carter K, DOrazio J
Exp Dermatol . 2017 Jan; 26(7):577-584. PMID: 28094871
Loss-of-function melanocortin 1 receptor (MC1R) polymorphisms are common in UV-sensitive fair-skinned individuals and are associated with blunted cAMP second messenger signalling and higher lifetime risk of melanoma because of diminished...