Stuart A Lipton
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Explore the profile of Stuart A Lipton including associated specialties, affiliations and a list of published articles.
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216
Citations
16763
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Recent Articles
21.
Kim K, Cho E, Eom J, Oh S, Nakamura T, Oh C, et al.
Cell Death Differ
. 2022 Apr;
29(11):2137-2150.
PMID: 35462559
Protein S-nitrosylation is known to regulate enzymatic function. Here, we report that nitric oxide (NO)-related species can contribute to Alzheimer's disease (AD) by S-nitrosylating the lysosomal protease cathepsin B (forming...
22.
Oh C, Nakamura T, Beutler N, Zhang X, Pina-Crespo J, Talantova M, et al.
bioRxiv
. 2022 Apr;
PMID: 35411336
Prevention of infection and propagation of SARS-CoV-2 is of high priority in the COVID-19 pandemic. Here, we describe S-nitrosylation of multiple proteins involved in SARS-CoV-2 infection, including angiotensin converting enzyme...
23.
Oh C, Dolatabadi N, Cieplak P, Diaz-Meco M, Moscat J, Nolan J, et al.
J Neurosci
. 2022 Feb;
42(14):3011-3024.
PMID: 35169022
Dysregulation of autophagic pathways leads to accumulation of abnormal proteins and damaged organelles in many neurodegenerative disorders, including Parkinson's disease (PD) and Lewy body dementia (LBD). Autophagy-related dysfunction may also...
24.
Satoh T, Trudler D, Oh C, Lipton S
Antioxidants (Basel)
. 2022 Jan;
11(1).
PMID: 35052628
Rosemary ( [family Lamiaceae]), an herb of economic and gustatory repute, is employed in traditional medicines in many countries. Rosemary contains carnosic acid (CA) and carnosol (CS), abietane-type phenolic diterpenes,...
25.
Trudler D, Ghatak S, Lipton S
Int J Mol Sci
. 2021 Aug;
22(15).
PMID: 34360966
Neurodegenerative diseases affect millions of people worldwide and are characterized by the chronic and progressive deterioration of neural function. Neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic...
26.
Nakamura T, Oh C, Zhang X, Lipton S
Free Radic Biol Med
. 2021 Jul;
172:562-577.
PMID: 34224817
Neurodegenerative disorders like Alzheimer's disease and Parkinson's disease are characterized by progressive degeneration of synapses and neurons. Accumulation of misfolded/aggregated proteins represents a pathological hallmark of most neurodegenerative diseases, potentially...
27.
Xian H, Liu Y, Rundberg Nilsson A, Gatchalian R, Crother T, Tourtellotte W, et al.
Immunity
. 2021 Jun;
54(7):1463-1477.e11.
PMID: 34115964
Acute respiratory distress syndrome (ARDS), an inflammatory condition with high mortality rates, is common in severe COVID-19, whose risk is reduced by metformin rather than other anti-diabetic medications. Detecting of...
28.
Nakamura T, Oh C, Zhang X, Tannenbaum S, Lipton S
Antioxid Redox Signal
. 2021 May;
35(7):531-550.
PMID: 33957758
Physiological concentrations of nitric oxide (NO) and related reactive nitrogen species (RNS) mediate multiple signaling pathways in the nervous system. During inflammaging (chronic low-grade inflammation associated with aging) and in...
29.
Doulias P, Nakamura T, Scott H, McKercher S, Sultan A, Deal A, et al.
J Neurovirol
. 2021 May;
27(3):379.
PMID: 33942273
No abstract available.
30.
Doulias P, Nakamura T, Scott H, McKercher S, Sultan A, Deal A, et al.
J Neurovirol
. 2021 Apr;
27(3):367-378.
PMID: 33876414
In the brain, both HIV-1 and methamphetamine (meth) use result in increases in oxidative and nitrosative stress. This redox stress is thought to contribute to the pathogenesis of HIV-associated neurocognitive...