Stuart A Lipton
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Explore the profile of Stuart A Lipton including associated specialties, affiliations and a list of published articles.
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216
Citations
16763
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Recent Articles
1.
Zhang X, Vlkolinsky R, Wu C, Dolatabadi N, Scott H, Prikhodko O, et al.
Proc Natl Acad Sci U S A
. 2025 Feb;
122(9):e2418179122.
PMID: 40014571
cAMP response element-binding protein (CREB)-regulated transcription coactivator 1 (CRTC1) plays an important role in synaptic plasticity, learning, and long-term memory formation through the regulation of neuronal activity-dependent gene expression, and...
2.
Oh C, Nakamura T, Zhang X, Lipton S
Neuron
. 2024 Nov;
112(23):3823-3850.
PMID: 39515322
Redox-mediated posttranslational modification, as exemplified by protein S-nitrosylation, modulates protein activity and function in both health and disease. Here, we review recent findings that show how normal aging, infection/inflammation, trauma,...
3.
Zhou H, Lin W, Labra S, Lipton S, Elman J, Schork N, et al.
IEEE/ACM Trans Comput Biol Bioinform
. 2024 Oct;
PP.
PMID: 39471117
Many traditional methods for analyzing gene-gene relationships focus on positive and negative correlations, both of which are a kind of 'symmetric' relationship. Biclustering is one such technique that typically searches...
4.
Son A, Kim H, Diedrich J, Bamberger C, McClatchy D, Lipton S, et al.
Nat Commun
. 2024 Oct;
15(1):9310.
PMID: 39468068
Mass spectrometry-based methods can provide a global expression profile and structural readout of proteins in complex systems. Preserving the in vivo conformation of proteins in their innate state is challenging...
5.
Trudler D, Ghatak S, Bula M, Parker J, Talantova M, Luevanos M, et al.
Mol Psychiatry
. 2024 Sep;
PMID: 39349966
MEF2C is a critical transcription factor in neurodevelopment, whose loss-of-function mutation in humans results in MEF2C haploinsufficiency syndrome (MHS), a severe form of autism spectrum disorder (ASD)/intellectual disability (ID). Despite...
6.
Ghatak S, Diedrich J, Talantova M, Bhadra N, Scott H, Sharma M, et al.
Adv Sci (Weinh)
. 2024 May;
11(29):e2400545.
PMID: 38773714
Standard single-cell (sc) proteomics of disease states inferred from multicellular organs or organoids cannot currently be related to single-cell physiology. Here, a scPatch-Clamp/Proteomics platform is developed on single neurons generated...
7.
Nakamura T, Lipton S
Mol Cell
. 2024 Jan;
84(2):191-193.
PMID: 38242098
In a recent study in Cell, Zhou et al. propose enzymatic transfer of nitric-oxide (NO)-related species from SNO-CoA to target proteins involved in insulin signaling; this function comprises an SNO-CoA-Assisted...
8.
Andreyev A, Yang H, Doulias P, Dolatabadi N, Zhang X, Luevanos M, et al.
Adv Sci (Weinh)
. 2024 Jan;
11(12):e2306469.
PMID: 38235614
In Alzheimer's disease (AD), dysfunctional mitochondrial metabolism is associated with synaptic loss, the major pathological correlate of cognitive decline. Mechanistic insight for this relationship, however, is still lacking. Here, comparing...
9.
Oh C, Nakamura T, Lipton S
Autophagy Rep
. 2023 Dec;
1(1):223-225.
PMID: 38098743
Autophagy (in the form of macroautophagy) is the major intracellular protein quality control system for removal of damaged organelles and abnormally aggregated proteins. We and others have shown that dysregulated...
10.
Oh C, Pina-Crespo J, Talantova M, Carnevale L, Stoneham C, Lewinski M, et al.
Nat Chem Biol
. 2023 Oct;
19(11):1306-1308.
PMID: 37798355
No abstract available.