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Steven W Magennis

Explore the profile of Steven W Magennis including associated specialties, affiliations and a list of published articles. Areas
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Articles 42
Citations 364
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Recent Articles
1.
Cadden G, Schloetel J, McKenzie G, Boocock M, Magennis S, Stark W
Nat Commun . 2024 Nov; 15(1):10407. PMID: 39613732
Serine recombinases are proposed to catalyse site-specific recombination by a unique mechanism called subunit rotation. Cutting and rejoining DNA occurs within an intermediate synaptic complex comprising a recombinase tetramer bound...
2.
Bailie A, Sansom H, Fisher R, Watabe R, Tor Y, Jones A, et al.
Phys Chem Chem Phys . 2024 Oct; 26(42):26823-26833. PMID: 39404501
Fluorescent base analogues (FBAs) are versatile nucleic acid labels that can replace a native nucleobase, while maintaining base pairing and secondary structure. Following the recent demonstration that free FBAs can...
3.
Cadden G, Wilken S, Magennis S
Nucleic Acids Res . 2024 Jul; 52(15):9317-9327. PMID: 39041420
An increasing number of human disorders are attributed to genomic expansions of short tandem repeats (STRs). Secondary DNA structures formed by STRs are believed to play an important role in...
4.
Dodds A, Sansom H, Magennis S, Sutherland A
Org Lett . 2023 Dec; 25(49):8942-8946. PMID: 38055619
Thiazoloindole α-amino acids have been synthesized in four steps from tryptophan using a dual-catalytic thiolation reaction and a copper-mediated intramolecular N-arylation process. Late-stage diversification of the thiazoloindole core with electron-deficient...
5.
Ploetz E, Ambrose B, Barth A, Borner R, Erichson F, Kapanidis A, et al.
Methods Appl Fluoresc . 2023 Sep; 12(1). PMID: 37726007
PIFE was first used as an acronym for protein-induced fluorescence enhancement, which refers to the increase in fluorescence observed upon the interaction of a fluorophore, such as a cyanine, with...
6.
Nilsson J, Benitez-Martin C, Sansom H, Pfeiffer P, Baladi T, Le H, et al.
Phys Chem Chem Phys . 2023 Jul; 25(30):20218-20224. PMID: 37475592
Fluorescent nucleobase analogues (FBAs) are established tools for studying oligonucleotide structure, dynamics and interactions, and have recently also emerged as an attractive option for labeling RNA-based therapeutics. A recognized drawback...
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Ploetz E, Ambrose B, Barth A, Borner R, Erichson F, Kapanidis A, et al.
ArXiv . 2023 Mar; PMID: 36866225
PIFE was first used as an acronym for protein-induced fluorescence enhancement, which refers to the increase in fluorescence observed upon the interaction of a fluorophore, such as a cyanine, with...
9.
Nobis D, Sansom H, Magennis S
Methods Appl Fluoresc . 2023 Jan; 11(1). PMID: 36595246
Multiphoton excitation of fluorescence has many potential advantages over resonant (one-photon) excitation, but the method has not found widespread use for ultrasensitive applications. We recently described an approach to the...
10.
Bianco S, Hu T, Henrich O, Magennis S
Biophys Rep (N Y) . 2022 Oct; 2(3):None. PMID: 36299495
It is unclear how the length of a repetitive DNA tract determines the onset and progression of repeat expansion diseases, but the dynamics of secondary DNA structures formed by repeat...