Steven S Gross
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Explore the profile of Steven S Gross including associated specialties, affiliations and a list of published articles.
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99
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4255
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Recent Articles
1.
Tang X, Pesola G, Chen Q, Miller D, Nagy L, McMullen M, et al.
Alcohol Clin Exp Res (Hoboken)
. 2025 Feb;
PMID: 40016864
Background: Chronic alcohol drinking causes hepatic vitamin A (retinoids and derivatives) decreases, which correlate with the progression and severity of alcohol-associated liver disease (ALD). However, the effects of short-term ethanol...
2.
Chen L, van der Veer B, Chen Q, Tsaniras S, Brangers W, Kwak H, et al.
EMBO Rep
. 2024 Nov;
26(1):175-199.
PMID: 39578553
Folic acid (FA) is well known to prevent neural tube defects (NTDs), but we do not know why many human NTD cases still remain refractory to FA supplementation. Here, we...
3.
van der Veer B, Chen L, Tsaniras S, Brangers W, Chen Q, Schroiff M, et al.
bioRxiv
. 2024 Jul;
PMID: 39026762
The etiology of neural tube defects (NTDs) involves complex gene-environmental interactions. Folic acid (FA) prevents NTDs, but the mechanisms remain poorly understood and at least 30% of human NTDs resist...
4.
Zhou D, Eraslan Z, Miller D, Taylor I, You J, Grondin S, et al.
Pigment Cell Melanoma Res
. 2024 Jun;
37(5):656-666.
PMID: 38844435
Melanosomal pH is important for the synthesis of melanin as the rate-limiting enzyme, tyrosinase, is very pH-sensitive. The soluble adenylyl cyclase (sAC) signaling pathway was recently identified as a regulator...
5.
Cheng H, Miller D, Southwell N, Porcari P, Fischer J, Taylor I, et al.
bioRxiv
. 2024 Feb;
PMID: 38370710
Mass spectrometry imaging (MSI) is a powerful technology used to define the spatial distribution and relative abundance of metabolites across tissue cryosections. While software packages exist for pixel-by-pixel individual metabolite...
6.
Dumelie J, Chen Q, Miller D, Attarwala N, Gross S, Jaffrey S
Nat Chem Biol
. 2023 Nov;
20(3):302-313.
PMID: 37973889
Proteins and RNA can phase separate from the aqueous cellular environment to form subcellular compartments called condensates. This process results in a protein-RNA mixture that is chemically different from the...
7.
Nader N, Assaf L, Zarif L, Halama A, Yadav S, Dib M, et al.
bioRxiv
. 2023 Oct;
PMID: 37905030
The steroid hormone progesterone (P4) regulates multiple aspects of reproductive and metabolic physiology. Classical P4 signaling operates through nuclear receptors that regulate transcription. In addition, P4 signals through membrane P4...
8.
Parchem J, Fan H, Mann L, Chen Q, Won J, Gross S, et al.
iScience
. 2023 Aug;
26(8):107424.
PMID: 37575192
Monochorionic-diamniotic twin pregnancies are susceptible to unique complications arising from a single placenta shared by two fetuses. Twin-twin transfusion syndrome (TTTS) is a constellation of disturbances caused by unequal blood...
9.
Southwell N, Primiano G, Nadkarni V, Attarwala N, Beattie E, Miller D, et al.
EMBO Mol Med
. 2023 May;
15(7):e16951.
PMID: 37222423
Mitochondrial diseases are a heterogeneous group of monogenic disorders that result from impaired oxidative phosphorylation (OXPHOS). As neuromuscular tissues are highly energy-dependent, mitochondrial diseases often affect skeletal muscle. Although genetic...
10.
van der Mijn J, Laursen K, Fu L, Khani F, Dow L, Nowak D, et al.
Sci Rep
. 2023 May;
13(1):8246.
PMID: 37217526
Genetically engineered mouse models (GEMMs) are important immunocompetent models for research into the roles of individual genes in cancer and the development of novel therapies. Here we use inducible CRISPR-Cas9...