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Steven Petratos

Explore the profile of Steven Petratos including associated specialties, affiliations and a list of published articles. Areas
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Articles 54
Citations 981
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Recent Articles
1.
Emamnejad R, Pagnin M, Petratos S
Neurosci Biobehav Rev . 2024 Jul; 164:105788. PMID: 38950685
Multiple sclerosis (MS) is an autoimmune disease, governed by oligodendrocyte (OL) dystrophy and central nervous system (CNS) demyelination manifesting variable neurological impairments. Mitochondrial mechanisms may drive myelin biogenesis maintaining the...
2.
Nheu D, Petratos S
Neurosci Biobehav Rev . 2024 Jun; 163:105767. PMID: 38885889
Multiple sclerosis (MS) is a severe neurological disorder that involves inflammation in the brain, spinal cord and optic nerve with key disabling neuropathological outcomes being axonal damage and demyelination. When...
3.
Ellen O, Ye S, Nheu D, Dass M, Pagnin M, Ozturk E, et al.
Int J Mol Sci . 2023 Jul; 24(13). PMID: 37446290
Multiple sclerosis (MS) is a heterogeneous disease of the central nervous system that is governed by neural tissue loss and dystrophy during its progressive phase, with complex reactive pathological cellular...
4.
Rashidbenam Z, Ozturk E, Pagnin M, Theotokis P, Grigoriadis N, Petratos S
Front Cell Neurosci . 2023 Jun; 17:1197492. PMID: 37361998
Multiple sclerosis (MS) can progress with neurodegeneration as a consequence of chronic inflammatory mechanisms that drive neural cell loss and/or neuroaxonal dystrophy in the central nervous system. Immune-mediated mechanisms can...
5.
Barmpagiannos K, Theotokis P, Petratos S, Pagnin M, Einstein O, Kesidou E, et al.
Healthcare (Basel) . 2023 Jun; 11(11). PMID: 37297725
Neuroglial cells, and especially astrocytes, constitute the most varied group of central nervous system (CNS) cells, displaying substantial diversity and plasticity during development and in disease states. The morphological changes...
6.
Ye S, Theotokis P, Lee J, Kim M, Nheu D, Ellen O, et al.
Brain Commun . 2023 Apr; 5(2):fcad108. PMID: 37091588
Nogo receptor 1 is the high affinity receptor for the potent myelin-associated inhibitory factors that make up part of the inflammatory extracellular milieu during experimental autoimmune encephalomyelitis. Signalling through the...
7.
Dermitzakis I, Manthou M, Meditskou S, Tremblay M, Petratos S, Zoupi L, et al.
Curr Issues Mol Biol . 2023 Mar; 45(3):2609-2628. PMID: 36975541
Microglia belong to tissue-resident macrophages of the central nervous system (CNS), representing the primary innate immune cells. This cell type constitutes ~7% of non-neuronal cells in the mammalian brain and...
8.
Nheu D, Ellen O, Ye S, Ozturk E, Pagnin M, Kertadjaja S, et al.
Cells . 2022 Dec; 11(23). PMID: 36497029
Current therapeutics targeting chronic phases of multiple sclerosis (MS) are considerably limited in reversing the neural damage resulting from repeated inflammation and demyelination insults in the multi-focal lesions. This inflammation...
9.
Emamnejad R, Dass M, Mahlis M, Bozkurt S, Ye S, Pagnin M, et al.
Front Pharmacol . 2022 Sep; 13:934971. PMID: 36133808
Multiple sclerosis (MS) is a heterogeneous autoimmune disease whereby the pathological sequelae evolve from oligodendrocytes (OLs) within the central nervous system and are targeted by the immune system, which causes...
10.
Dermitzakis I, Manthou M, Meditskou S, Miliaras D, Kesidou E, Boziki M, et al.
Curr Issues Mol Biol . 2022 Jul; 44(7):3208-3237. PMID: 35877446
The mammalian central nervous system (CNS) coordinates its communication through saltatory conduction, facilitated by myelin-forming oligodendrocytes (OLs). Despite the fact that neurogenesis from stem cell niches has caught the majority...