Steven Petratos
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Explore the profile of Steven Petratos including associated specialties, affiliations and a list of published articles.
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54
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981
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Recent Articles
11.
Damianidou O, Theotokis P, Grigoriadis N, Petratos S
Int J Med Sci
. 2022 Jan;
19(1):164-174.
PMID: 34975310
Over the past two decades, the development of targeted immunotherapeutics for relapsing-remitting multiple sclerosis has been successfully orchestrated through the efficacious modulation of neuroinflammatory outcomes demonstrated in the experimental autoimmune...
12.
Theotokis P, Kesidou E, Mitsiadou D, Petratos S, Damianidou O, Boziki M, et al.
Brain Pathol
. 2021 Nov;
32(4):e13040.
PMID: 34845781
Experimental autoimmune encephalomyelitis (EAE) is a basic and reliable model used to study clinical and pathological hallmarks of multiple sclerosis (MS) in rodents. Several studies suggest neural precursor cells (NPCs)...
13.
Pagnin M, Dekiwadia C, Petratos S, Richardson S
Neurosci Lett
. 2021 Oct;
766:136287.
PMID: 34634393
Thyroid hormones (THs) impact nearly every tissue in the body, including the adult and developing central nervous system. The distribution of THs around the body is facilitated by specific TH...
14.
Bakhuraysah M, Theotokis P, Lee J, Alrehaili A, Aui P, Figgett W, et al.
Sci Rep
. 2021 Feb;
11(1):2890.
PMID: 33536561
We have previously reported evidence that Nogo-A activation of Nogo-receptor 1 (NgR1) can drive axonal dystrophy during the neurological progression of experimental autoimmune encephalomyelitis (EAE). However, the B-cell activating factor...
15.
Petratos S, Theotokis P, Kim M, Azari M, Lee J
Front Cell Neurosci
. 2020 Aug;
14:227.
PMID: 32848619
Myelin is a dynamic membrane that is important for coordinating the fast propagation of action potentials along small or large caliber axons (0.1-10 μm) some of which extend the entire...
16.
Alshehri B, Pagnin M, Lee J, Petratos S, Richardson S
Sci Rep
. 2020 Mar;
10(1):4189.
PMID: 32144308
Transthyretin (TTR) is a protein that binds and distributes thyroid hormones (THs) in blood and cerebrospinal fluid. Previously, two reports identified TTR null mice as hypothyroid in the central nervous...
17.
Chiha W, Bartlett C, Petratos S, Fitzgerald M, Harvey A
Exp Neurol
. 2020 Jan;
326:113167.
PMID: 31904385
Secondary degeneration following an initial injury to the central nervous system (CNS) results in increased tissue loss and is associated with increasing functional impairment. Unilateral partial dorsal transection of the...
18.
Kim M, Petratos S
Stem Cells Int
. 2019 Jun;
2019:5496891.
PMID: 31182964
Oligodendrocytes are supporting glial cells that ensure the metabolism and homeostasis of neurons with specific synaptic axoglial interactions in the central nervous system. These require key myelinating glial trophic signals...
19.
Lee J, Kim M, Thomas S, Oorschot V, Ramm G, Aui P, et al.
J Neurosci
. 2019 May;
39(28):5562-5580.
PMID: 31061088
We previously identified that allele deletion limits the severity of experimental autoimmune encephalomyelitis (EAE) by preserving axonal integrity. However, whether this favorable outcome observed in EAE is a consequence of...
20.
Kim M, Kang J, Theotokis P, Grigoriadis N, Petratos S
Cells
. 2018 Dec;
8(1).
PMID: 30577457
The current landscape of therapeutics designed to treat multiple sclerosis (MS) and its pathological sequelae is saturated with drugs that modify disease course and limit relapse rates. While these small...