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Steven Paraskevas

Explore the profile of Steven Paraskevas including associated specialties, affiliations and a list of published articles. Areas
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Articles 65
Citations 770
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Recent Articles
1.
Shamseddin M, Paraskevas S, Mainra R, Maru K, Piggott B, Jagusic D, et al.
Can J Kidney Health Dis . 2024 Dec; 11:20543581241306811. PMID: 39735689
Purpose: Highly sensitized patients (HSPs) with kidney failure have limited access to kidney transplantation and poorer post-transplant outcomes. Prioritizing HSPs in kidney allocation systems and expanding the pool of deceased...
2.
Yitayew M, Gasparrini M, Li L, Paraskevas S, Tabrizian M
Int J Biol Macromol . 2024 Aug; 278(Pt 4):134960. PMID: 39179080
Multilayer conformal coatings have been shown to provide a nanoscale barrier between cells and their environment with adequate stability, while regulating the diffusion of nutrition and waste across the cell...
3.
Negi S, Rutman A, Saw C, Paraskevas S, Tchervenkov J
Front Transplant . 2024 Jul; 3:1336563. PMID: 38993777
Introduction: Sensitization to donor human leukocyte antigen (HLA) molecules prior to transplantation is a significant risk factor for delayed access to transplantation and to long-term outcomes. Memory T cells and...
4.
Fouda A, Maallah M, Kouyoumdjian A, Negi S, Paraskevas S, Tchervenkov J
Commun Biol . 2024 Apr; 7(1):454. PMID: 38609465
Chronic antibody mediated rejection (AMR) is the major cause of solid organ graft rejection. Th17 contributes to AMR through the secretion of IL17A, IL21 and IL22. These cytokines promote neutrophilic...
5.
Sandal S, Cantarovich M, Cardinal H, Ramankumar A, Senecal L, Collette S, et al.
Kidney360 . 2023 May; 4(6):e809-e816. PMID: 37211638
No abstract available.
6.
Fouda A, Negi S, Zaremba O, Gaidar R, Moroz Y, Rusanov E, et al.
J Med Chem . 2023 May; 66(11):7355-7373. PMID: 37172324
Retinoic acid receptor-related orphan receptor γt (RORγt) is a nuclear receptor that is expressed in a variety of tissues and is a potential drug target for the treatment of inflammatory...
7.
Zaminpeyma R, Claus M, Paraskevas S, Court O, Tchervenkov J, Andalib A
Surg Endosc . 2022 Aug; 37(1):494-502. PMID: 36002684
Background: Kidney transplantation (KT) is the preferred therapy for end-stage renal disease (ESRD). While a major cause for ESRD, obesity is also a key obstacle to candidacy for KT. Bariatric...
8.
Kouyoumdjian A, Tchervenkov J, Paraskevas S
Front Immunol . 2022 Jul; 13:903913. PMID: 35874723
Tumor necrosis factor receptor 2 (TNFR2) has been shown to play a crucial role in CD4+ T regulatory cells (CD4+Tregs) expansion and suppressive function. Increasing evidence has also demonstrated its...
9.
Rutman A, Negi S, Saberi N, Khan K, Tchervenkov J, Paraskevas S
Front Immunol . 2022 Mar; 13:784374. PMID: 35281056
Delayed graft function (DGF) in kidney transplantation is associated with ischemic injury and carries long term functional and immunological risks. Extracellular vesicles (EV) released from allografts may signal a degree...
10.
Yanev I, Gagnon M, Cheng M, Paraskevas S, Kumar D, Dragomir A, et al.
Can J Kidney Health Dis . 2021 Sep; 8:20543581211040332. PMID: 34540237
Background: The coronavirus disease 2019 (COVID-19) pandemic impacted transplant programs across Canada. Objective: We evaluated the implications of delays in transplantation among Canadian end-stage kidney disease (ESKD) patients to allow...