Steven Marston
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Explore the profile of Steven Marston including associated specialties, affiliations and a list of published articles.
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35
Citations
984
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Recent Articles
1.
Marston S, Pinto J
Front Cardiovasc Med
. 2023 Jan;
9:1080965.
PMID: 36698941
In cardiac muscle the action of adrenaline on β1 receptors of heart muscle cells is essential to adjust cardiac output to the body's needs. Adrenergic activation leads to enhanced contractility...
2.
Marston S
J Muscle Res Cell Motil
. 2022 Sep;
44(3):201-208.
PMID: 36131171
Ca acts on troponin and tropomyosin to switch the thin filament on and off, however in cardiac muscle a more graded form of regulation is essential to tailor cardiac output...
3.
Marston S
Front Physiol
. 2022 Feb;
12:817036.
PMID: 35153821
Contractility, the generation of force and movement by molecular motors, is the hallmark of all muscles, including striated muscle. Contractility can be studied at every level of organization from a...
4.
Alsulami K, Marston S
Int J Mol Sci
. 2020 Dec;
21(24).
PMID: 33339418
Hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) are the most prevalent forms of the chronic and progressive pathological condition known as cardiomyopathy. These diseases have different aetiologies; however, they share...
5.
Marston S, Jacques A, Bayliss C, Dyer E, Memo M, Papadaki M, et al.
Biophys Rev
. 2020 Jul;
12(4):799-803.
PMID: 32691299
Human heart samples from the Sydney Heart Bank have become a de facto standard against which others can be measured. Crucially, the heart bank contains a lot of donor heart...
6.
Copeland O, Messer A, Jabbour A, Poggesi C, Prasad S, Marston S
Front Physiol
. 2020 Apr;
11:241.
PMID: 32265736
In previous studies of septal heart muscle from HCM patients with hypertrophic obstructive cardiomyopathy (HOCM, LVOT gradient 50-120 mmHg) we found that the level of phosphorylation of troponin I (TnI)...
7.
Marston S
J Muscle Res Cell Motil
. 2019 Jun;
40(2):69-76.
PMID: 31228047
The study of muscle and contractility is an unusual scientific endeavour since it has from the start been focussed on one problem-What makes muscle work?-and yet has needed a vast...
8.
Marston S, Zamora J
J Muscle Res Cell Motil
. 2019 Apr;
41(1):71-89.
PMID: 31030382
The molecular mechanism by which Ca binding and phosphorylation regulate muscle contraction through Troponin is not yet fully understood. Revealing the differences between the relaxed and active structure of cTn,...
9.
Marston S
Int J Mol Sci
. 2018 Jul;
19(7).
PMID: 29997361
The discovery that mutations in myosin and actin genes, together with mutations in the other components of the muscle sarcomere, are responsible for a range of inherited muscle diseases (myopathies)...
10.
Marston S
Biophys Rev
. 2017 May;
9(3):239-243.
PMID: 28510120
The inherited cardiomyopathies, hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM) and left ventricular non-compaction (LVNC), have been frequently associated with mutations in sarcomeric proteins. In recent years, advances in DNA sequencing...