Steven M Opal
Overview
Explore the profile of Steven M Opal including associated specialties, affiliations and a list of published articles.
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Articles
168
Citations
23140
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Recent Articles
1.
Cross A, Opal S, Palardy J, Shridhar S, Baliban S, Scott A, et al.
Innate Immun
. 2021 Apr;
27(3):266-274.
PMID: 33858243
Despite the dramatic increase in antimicrobial resistance, there is a dearth of antibiotics in development and few pharmaceutical companies working in the field. Further, any new antibiotics are likely to...
2.
Shoji H, Opal S
Int J Mol Sci
. 2021 Mar;
22(4).
PMID: 33672437
Endotoxin removal therapy with polymyxin B immobilized fiber column (PMX) has been clinically applied for sepsis and septic shock patients since 1994. The effectiveness and usefulness of this therapy have...
3.
Carlet J, Payen D, Opal S
Lancet
. 2020 Oct;
396(10259):e61-e62.
PMID: 33045189
No abstract available.
4.
Tannous A, Levinson S, Bolognese J, Opal S, DiNubile M
Antimicrob Agents Chemother
. 2020 Jul;
64(10).
PMID: 32690640
There remains an unmet need to address the substantial morbidity and mortality associated with severe community-acquired pneumonia (sCAP). Recombinant human plasma gelsolin (rhu-pGSN) improves disease outcomes in diverse animal models...
5.
6.
Hotchkiss R, Opal S
N Engl J Med
. 2020 Mar;
382(13):1270-1272.
PMID: 32212525
No abstract available.
7.
Fedson D, Opal S, Rordam O
mBio
. 2020 Mar;
11(2).
PMID: 32198163
Patients with COVID-19 infection are at risk of acute respiratory disease syndrome (ARDS) and death. The tissue receptor for COVID-19 is ACE2, and higher levels of ACE2 can protect against...
8.
Opal S, Wittebole X
Crit Care Clin
. 2019 Nov;
36(1):11-22.
PMID: 31733673
The role of biomarkers for detection of sepsis has come a long way. Molecular biomarkers are taking front stage at present, but machine learning and other computational measures using bigdata...
9.
Laterre P, Levy M, Wittebole X, Dugernier T, Francois B, Opal S
Anaesth Crit Care Pain Med
. 2019 Oct;
38(5):419-421.
PMID: 31585759
No abstract available.
10.
Laterre P, Berry S, Blemings A, Carlsen J, Francois B, Graves T, et al.
JAMA
. 2019 Oct;
322(15):1476-1485.
PMID: 31577035
Importance: Norepinephrine, the first-line vasopressor for septic shock, is not always effective and has important catecholaminergic adverse effects. Selepressin, a selective vasopressin V1a receptor agonist, is a noncatecholaminergic vasopressor that...