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Steven M Hill

Explore the profile of Steven M Hill including associated specialties, affiliations and a list of published articles. Areas
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Articles 69
Citations 2571
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Recent Articles
1.
Tivey A, Lee R, Clipson A, Hill S, Lorigan P, Rothwell D, et al.
Cell Rep Med . 2024 Sep; 5(9):101736. PMID: 39293399
Treatments for cancer patients are becoming increasingly complex, and there is a growing desire from clinicians and patients for biomarkers that can account for this complexity to support informed decisions...
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Rahman M, Harrison E, Biggs H, Seikus C, Elliott P, Breen G, et al.
Nat Med . 2024 May; 30(6):1739-1748. PMID: 38745010
A leading explanation for translational failure in neurodegenerative disease is that new drugs are evaluated late in the disease course when clinical features have become irreversible. Here, to address this...
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Conway A, Pearce S, Clipson A, Hill S, Chemi F, Slane-Tan D, et al.
Nat Commun . 2024 Apr; 15(1):3292. PMID: 38632274
Cancers of Unknown Primary (CUP) remains a diagnostic and therapeutic challenge due to biological heterogeneity and poor responses to standard chemotherapy. Predicting tissue-of-origin (TOO) molecularly could help refine this diagnosis,...
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Dauchy R, Hill S, Blask D
Methods Mol Biol . 2022 Sep; 2550:489-496. PMID: 36180716
The tissue-isolated tumor model permits the investigation of melatonin's influence on human tumor growth and metabolism in laboratory rats in vivo. Here we describe a unique surgical technique for implanting...
6.
Dauchy R, Hill S, Blask D
Methods Mol Biol . 2022 Sep; 2550:477-488. PMID: 36180715
The tissue-isolated human tumor perfusion methodology enables the elucidation of physiological melatonin's oncostatic impact on cancer metabolism and physiology. Here we describe an apparatus and surgical technique for perfusing tissue-isolated...
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Chemi F, Pearce S, Clipson A, Hill S, Conway A, Richardson S, et al.
Nat Cancer . 2022 Aug; 3(10):1260-1270. PMID: 35941262
Small cell lung cancer (SCLC) is characterized by morphologic, epigenetic and transcriptomic heterogeneity. Subtypes based upon predominant transcription factor expression have been defined that, in mouse models and cell lines,...
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Howlett J, Hill S, Ritchie C, Tom B
Front Big Data . 2021 Sep; 4:676168. PMID: 34490422
A key challenge for the secondary prevention of Alzheimer's dementia is the need to identify individuals early on in the disease process through sensitive cognitive tests and biomarkers. The European...
9.
Dauchy E, Dauchy R, Tirrell R, Davidson L, Hill S, Sauer L, et al.
Comp Med . 2021 Jun; 71(4):309-317. PMID: 34187631
Melatonin, the circadian nighttime neurohormone, and eicosapentaenoic acid (EPA) and docosahexaenoic acids (DHA), which are omega-3 fatty acids (FA) found in high concentrations in fish oil (FO) and plants, abrogate...
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Voros G, Dauchy R, Myers L, Hill S, Blask D, Dobek G
J Am Assoc Lab Anim Sci . 2021 Mar; 60(3):259-271. PMID: 33673880
Light has been a crucial part of everyday life since the beginning of time. Most recently, light-emitting diode (LED) light enriched in the blue-appearing portion of the visible spectrum (465...