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Steven L Gonias

Explore the profile of Steven L Gonias including associated specialties, affiliations and a list of published articles. Areas
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Articles 109
Citations 3490
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Recent Articles
1.
Martellucci S, Flutsch A, Carter M, Norimoto M, Pizzo D, Mantuano E, et al.
Glia . 2024 Feb; 72(5):916-937. PMID: 38372375
Schwann cells (SCs) undergo phenotypic transformation and then orchestrate nerve repair following PNS injury. The ligands and receptors that activate and sustain SC transformation remain incompletely understood. Proteins released by...
2.
Arvisais-Anhalt S, Gonias S, Murray S
Acad Pathol . 2024 Jan; 11(1):100101. PMID: 38292297
Artificial intelligence and machine learning have numerous applications in pathology and laboratory medicine. The release of ChatGPT prompted speculation regarding the potentially transformative role of large-language models (LLMs) in academic...
3.
Matteson N, W Hassler G, Kurzban E, Schwab M, Perkins S, Gangavarapu K, et al.
Cell . 2023 Dec; 186(26):5690-5704.e20. PMID: 38101407
The maturation of genomic surveillance in the past decade has enabled tracking of the emergence and spread of epidemics at an unprecedented level. During the COVID-19 pandemic, for example, genomic...
4.
Mantuano E, Zampieri C, Azmoon P, Gunner C, Heye K, Gonias S
JCI Insight . 2023 Jun; 8(15). PMID: 37368488
Low-density lipoprotein receptor-related protein-1 (LRP1) functions as a receptor for nonpathogenic cellular prion protein (PrPC), which is released from cells by ADAM (a disintegrin and metalloproteinase domain) proteases or in...
5.
Gunner C, Azmoon P, Mantuano E, Das L, Zampieri C, Pizzo S, et al.
J Cell Biochem . 2023 Mar; 124(5):743-752. PMID: 36947703
Glucose-regulated protein-78 (Grp78) is an endoplasmic reticulum chaperone, which is secreted by cells and associates with cell surfaces, where it functions as a receptor for activated α -macroglobulin (α M)...
6.
Mantuano E, Azmoon P, Banki M, Gunner C, Gonias S
Sci Rep . 2022 Oct; 12(1):17594. PMID: 36266319
LDL Receptor-related Protein-1 (LRP1/CD91) binds diverse ligands, many of which activate cell-signaling. Herein, we compared three LRP1 ligands that inhibit inflammatory responses triggered by lipopolysaccharide (LPS), including: enzymatically-inactive tissue-type plasminogen...
7.
Gonias S, Campana W
Neural Regen Res . 2022 Jul; 18(2):325-326. PMID: 35900418
No abstract available.
8.
Karthikeyan S, Levy J, de Hoff P, Humphrey G, Birmingham A, Jepsen K, et al.
Nature . 2022 Jul; 609(7925):101-108. PMID: 35798029
As SARS-CoV-2 continues to spread and evolve, detecting emerging variants early is critical for public health interventions. Inferring lineage prevalence by clinical testing is infeasible at scale, especially in areas...
9.
Karthikeyan S, Levy J, de Hoff P, Humphrey G, Birmingham A, Jepsen K, et al.
medRxiv . 2022 Apr; PMID: 35411350
As SARS-CoV-2 continues to spread and evolve, detecting emerging variants early is critical for public health interventions. Inferring lineage prevalence by clinical testing is infeasible at scale, especially in areas...
10.
Gonias S, Banki M, Azmoon P, Romero H, Sigurdson C, Mantuano E, et al.
J Biol Chem . 2022 Jan; 298(3):101642. PMID: 35090893
Exosomes and other extracellular vesicles (EVs) participate in cell-cell communication. Herein, we isolated EVs from human plasma and demonstrated that these EVs activate cell signaling and promote neurite outgrowth in...