Steven K Nordeen
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Explore the profile of Steven K Nordeen including associated specialties, affiliations and a list of published articles.
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25
Citations
812
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Recent Articles
11.
Cochrane D, Spoelstra N, Howe E, Nordeen S, Richer J
Mol Cancer Ther
. 2009 May;
8(5):1055-66.
PMID: 19435871
The transcription factor ZEB1 is normally not expressed in epithelial cells. When inappropriately expressed in carcinomas, ZEB1 initiates epithelial to mesenchymal transition due to its ability to repress E-cadherin and...
12.
Mao C, Patterson N, Cherian M, Aninye I, Zhang C, Montoya J, et al.
J Biol Chem
. 2008 Mar;
283(19):12819-30.
PMID: 18337247
Estrogen receptor alpha (ERalpha) plays an important role in several human cancers. Most current ERalpha antagonists bind in the receptor ligand binding pocket and compete for binding with estrogenic ligands....
13.
Flaig T, Nordeen S, Lucia M, Harrison G, Glode L
J Urol
. 2007 Mar;
177(4):1229-37.
PMID: 17382696
Purpose: The use of prostate specific antigen screening to diagnose and monitor prostate cancer is associated with well-known shortcomings. A 2-day Prostate Cancer Biomarker Conference was convened to identify promising...
14.
Wang S, Zhang C, Nordeen S, Shapiro D
J Biol Chem
. 2006 Dec;
282(5):2765-75.
PMID: 17135255
Binding of full-length P160 coactivators to hormone response element-steroid receptor complexes has been difficult to investigate in vitro. Here, we report a new application of our recently described fluorescence anisotropy...
15.
Lambert J, Kelly J, Shim M, Huffer W, Nordeen S, Baek S, et al.
J Cell Physiol
. 2006 Jun;
208(3):566-74.
PMID: 16741990
The secosteroid hormone 1alpha, 25-dihydroxyvitamin D3 (1,25D) has been shown to regulate the growth and differentiation of human prostate cancer (PCa) cells, although the precise molecular mechanisms mediating these effects...
16.
Hedlund T, Van Bokhoven A, Johannes W, Nordeen S, Ogden L
Prostate
. 2005 Dec;
66(5):557-66.
PMID: 16372328
Background: The differential intestinal metabolism of the soy isoflavones is likely to influence the ability of soy to prevent prostate cancer. While daidzein, genistein, and equol have direct antiproliferative effects...
17.
Blackman B, Russell T, Nordeen S, Medina D, Neville M
Breast Cancer Res
. 2005 Mar;
7(2):R248-55.
PMID: 15743505
Introduction: Claudins, membrane-associated tetraspanin proteins, are normally associated with the tight junctions of epithelial cells where they confer a variety of permeability properties to the transepithelial barrier. One member of...
18.
Wang S, Ahn B, Harris R, Nordeen S, Shapiro D
Biotechniques
. 2004 Nov;
37(5):807-8, 810-7.
PMID: 15560136
To analyze the interactions of steroid/nuclear hormone receptors with their DNA response elements, we used ultra low-volume microplates to develop a simple and rapid fluorescence anisotropy assay. The novel fluorescence...
19.
Thackray V, Toft D, Nordeen S
Mol Endocrinol
. 2003 Oct;
17(12):2543-53.
PMID: 14551264
To elucidate the earliest molecular steps in the activation of transcription by the progesterone receptor (PR), we investigated its activity in a cell-free transcription system utilizing chromatin templates. PR prepared...
20.
Miller G, Miller H, Van Bokhoven A, Lambert J, Werahera P, Schirripa O, et al.
Cancer Res
. 2003 Oct;
63(18):5879-88.
PMID: 14522913
Dysregulation of HOX gene expression has been implicated as a factor in malignancies for a number of years. However, no consensus has emerged regarding specific causative genes. Using a degenerate...