Steven J Ressler
Overview
Explore the profile of Steven J Ressler including associated specialties, affiliations and a list of published articles.
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14
Citations
490
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Recent Articles
1.
Strand D, Liang Y, Yang F, Barron D, Ressler S, Schauer I, et al.
Am J Clin Exp Urol
. 2014 Nov;
2(3):239-48.
PMID: 25374926
Transforming Growth Factor-β (TGF-β) regulates the reactive stroma microenvironment associated with most carcinomas and mediates expression of many stromal derived factors important for tumor progression, including FGF-2 and CTGF. TGF-β...
2.
Kim W, Barron D, San Martin R, Chan K, Tran L, Yang F, et al.
Proc Natl Acad Sci U S A
. 2014 Oct;
111(46):16389-94.
PMID: 25313057
Myofibroblasts are a key cell type in wound repair, cardiovascular disease, and fibrosis and in the tumor-promoting microenvironment. The high accumulation of myofibroblasts in reactive stroma is predictive of the...
3.
Ressler S, Dang T, Wu S, Tse D, Gilbert B, Vyakarnam A, et al.
Am J Pathol
. 2014 Sep;
184(11):2951-64.
PMID: 25219356
WFDC1/ps20 is a whey acidic protein four-disulfide core member that exhibits diverse growth and immune-associated functions in vitro. In vivo functions are unknown, although WFDC1 is lower in reactive stroma....
4.
San Martin R, Barron D, Tuxhorn J, Ressler S, Hayward S, Shen X, et al.
Am J Pathol
. 2014 Apr;
184(6):1860-70.
PMID: 24713391
Reactive stroma co-evolves with cancer, exhibiting tumor-promoting properties. It is also evident at sites of wound repair and fibrosis, playing a key role in tissue homeostasis. The specific cell types...
5.
Yang F, Zhang Y, Ressler S, Ittmann M, Ayala G, Dang T, et al.
Cancer Res
. 2013 Apr;
73(12):3716-24.
PMID: 23576558
The fibroblast growth factor receptor 1 (FGFR1) is ectopically expressed in prostate carcinoma cells, but its functional contributions are undefined. In this study, we report the evaluation of a tissue-specific...
6.
Rogers E, Wang B, Cui Z, Rowley D, Ressler S, Vyakarnam A, et al.
Antiviral Res
. 2012 Sep;
96(2):158-68.
PMID: 22960155
The whey acidic protein family member, WFDC1/ps20 is a permissivity factor in HIV infection. Herein we describe a contrasting role for ps20 in limiting MHV-1 infection. Intranasal MHV-1 infection produces...
7.
Ressler S, Rowley D
Biochem Soc Trans
. 2011 Sep;
39(5):1455-9.
PMID: 21936833
The present evaluates the key features of the WFDC1 [WAP (whey acidic protein) four disulfide core 1] gene that encodes ps20 (20 kDa prostate stromal protein), a member of the...
8.
Barron D, Strand D, Ressler S, Dang T, Hayward S, Yang F, et al.
PLoS One
. 2010 Nov;
5(10):e13751.
PMID: 21060787
TGF-β1 is overexpressed in wound repair and in most proliferative disorders including benign prostatic hyperplasia and prostate cancer. The stromal microenvironment at these sites is reactive and typified by altered...
9.
Schauer I, Ressler S, Rowley D
Prostate
. 2008 Nov;
69(4):373-84.
PMID: 19021203
Background: Interleukin-8 (IL-8) is upregulated in fibrotic and malignant diseases and is a key mediator of proliferative responses. Elevated IL-8 was recently correlated with benign prostatic hyperplasia epithelium and a...
10.
Schauer I, Ressler S, Tuxhorn J, Dang T, Rowley D
Urology
. 2008 Mar;
72(1):205-13.
PMID: 18314176
Objectives: Numerous inflammatory diseases display elevated interleukin (IL)-8, and most are associated with a reactive stroma. IL-8 expression is also elevated in benign prostatic hyperplasia (BPH), yet little is known...