Steven D Young
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Explore the profile of Steven D Young including associated specialties, affiliations and a list of published articles.
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22
Citations
479
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Recent Articles
1.
Noona S, Young S, Weber M, El Moheb M, Norman A, Wisniewski A, et al.
J Thorac Cardiovasc Surg
. 2024 Aug;
PMID: 39153715
Objective: The study objective was to evaluate short-term outcomes and statewide practice patterns of prophylactic left atrial appendage ligation in patients undergoing coronary artery bypass grafting without preoperative atrial fibrillation....
2.
Wisniewski A, Young S, Do-Nguyen C, Hawkins R, Romano M, Teman N, et al.
Innovations (Phila)
. 2024 Jan;
19(1):64-71.
PMID: 38284330
Objective: Psoas muscle size is a reliable marker of sarcopenia and frailty that correlates with adverse outcomes after cardiac surgery. However, its use in mitral and minimally invasive cardiac surgery...
3.
Young A, Young B, Young S, Brundage A, Koyada P, Cramer C, et al.
Am Surg
. 2023 Sep;
90(3):427-435.
PMID: 37703078
Background: We hypothesized that the addition of a third-level trauma activation would improve outcomes by formalizing an evaluation process for patients in need of urgent evaluation who did not meet...
4.
Larkin E, Jones M, Young S, Young J
Injury
. 2022 May;
53(9):3059-3064.
PMID: 35623955
Trauma scoring systems were created to predict mortality and enhance triage capabilities. However, efficacy of scoring systems to predict mortality and accuracy of originally reported severity thresholds remains uncertain. A...
5.
Dietch Z, Young J, Young S
Am Surg
. 2016 Jul;
82(7):644-8.
PMID: 27457865
We examined financial data from a University Level I Trauma Center from 1994 to 2014. We sought to investigate the hypothesis that lower injury severity correlates with increased profitability. We...
6.
Roecker A, Reger T, Mattern M, Mercer S, Bergman J, Schreier J, et al.
Bioorg Med Chem Lett
. 2014 Sep;
24(20):4884-90.
PMID: 25248679
Orexin receptor antagonists have demonstrated clinical utility for the treatment of insomnia. The majority of clinical efforts to date have focused on the development of dual orexin receptor antagonists (DORAs),...
7.
Roecker A, Mercer S, Schreier J, Cox C, Fraley M, Steen J, et al.
ChemMedChem
. 2013 Dec;
9(2):311-22.
PMID: 24376006
The field of small-molecule orexin antagonist research has evolved rapidly in the last 15 years from the discovery of the orexin peptides to clinical proof-of-concept for the treatment of insomnia....
8.
Mercer S, Roecker A, Garson S, Reiss D, Harrell C, Murphy K, et al.
Bioorg Med Chem Lett
. 2013 Nov;
23(24):6620-4.
PMID: 24215892
The orexin (or hypocretin) system has been identified as a novel target for the treatment of insomnia due to the wealth of biological and genetic data discovered over the past...
9.
Layton M, Kelly 3rd M, Rodzinak K, Sanderson P, Young S, Bednar R, et al.
ACS Chem Neurosci
. 2012 Jul;
2(7):352-62.
PMID: 22816022
A series of 3-substituted aminocyclopentanes has been identified as highly potent and selective NR2B receptor antagonists. Incorporation of a 1,2,4-oxadiazole linker and substitution of the pendant phenyl ring led to...
10.
Coleman P, Schreier J, Cox C, Breslin M, Whitman D, Bogusky M, et al.
ChemMedChem
. 2012 Feb;
7(3):415-24, 337.
PMID: 22307992
Insomnia is a common disorder that can be comorbid with other physical and psychological illnesses. Traditional management of insomnia relies on general central nervous system (CNS) suppression using GABA modulators....