Steven C Wilson
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Explore the profile of Steven C Wilson including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
263
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Recent Articles
1.
Abhiraman G, Householder K, Rodriguez G, Glassman C, Saxton R, Breuer C, et al.
Nat Commun
. 2025 Mar;
16(1):2432.
PMID: 40069219
Cytokines are signaling molecules that coordinate complex immune processes and are frequently dysregulated in disease. While cytokine blockade has become a common therapeutic modality, cytokine agonism has had limited utility...
2.
Householder K, Xiang X, Jude K, Deng A, Obenaus M, Wilson S, et al.
bioRxiv
. 2025 Jan;
PMID: 39763827
T cell receptor (TCR) mimics offer a promising platform for tumor-specific targeting of peptide-MHC in cancer immunotherapy. Here, we designed a α-helical TCR mimic (TCRm) specific for the NY-ESO-1 peptide...
3.
Caveney N, Rodriguez G, Pollmann C, Meyer T, Borowska M, Wilson S, et al.
Mol Cell
. 2024 Apr;
84(10):1995-2005.e7.
PMID: 38614096
Cytokines regulate immune responses by binding to cell surface receptors, including the common subunit beta (βc), which mediates signaling for GM-CSF, IL-3, and IL-5. Despite known roles in inflammation, the...
4.
Tsutsumi N, Masoumi Z, James S, Tucker J, Winkelmann H, Grey W, et al.
Cell
. 2023 Aug;
186(19):4189-4203.e22.
PMID: 37633268
Thrombopoietin (THPO or TPO) is an essential cytokine for hematopoietic stem cell (HSC) maintenance and megakaryocyte differentiation. Here, we report the 3.4 Å resolution cryoelectron microscopy structure of the extracellular...
5.
Siepe D, Henneberg L, Wilson S, Hess G, Bassik M, Zinn K, et al.
Elife
. 2022 Sep;
11.
PMID: 36178190
Secreted proteins, which include cytokines, hormones, and growth factors, are extracellular ligands that control key signaling pathways mediating cell-cell communication within and between tissues and organs. Many drugs target secreted...
6.
Wilson S, Caveney N, Yen M, Pollmann C, Xiang X, Jude K, et al.
Nature
. 2022 Jul;
609(7927):622-629.
PMID: 35863378
The IL-17 family of cytokines and receptors have central roles in host defence against infection and development of inflammatory diseases. The compositions and structures of functional IL-17 family ligand-receptor signalling...
7.
Structures of neurexophilin-neurexin complexes reveal a regulatory mechanism of alternative splicing
Wilson S, White K, Zhou Q, Pfuetzner R, Choi U, Sudhof T, et al.
EMBO J
. 2019 Oct;
38(22):e101603.
PMID: 31566781
Neurexins are presynaptic, cell-adhesion molecules that specify the functional properties of synapses via interactions with trans-synaptic ligands. Neurexins are extensively alternatively spliced at six canonical sites that regulate multifarious ligand...
8.
Cai F, Bernstein S, Wilson S, Kerfeld C
Plant Physiol
. 2016 Jan;
170(3):1868-77.
PMID: 26792123
Spatial segregation of metabolism, such as cellular-localized CO2 fixation in C4 plants or in the cyanobacterial carboxysome, enhances the activity of inefficient enzymes by selectively concentrating them with their substrates....
9.
Cameron J, Wilson S, Bernstein S, Kerfeld C
Cell
. 2013 Nov;
155(5):1131-40.
PMID: 24267892
The carboxysome is a protein-based organelle for carbon fixation in cyanobacteria, keystone organisms in the global carbon cycle. It is composed of thousands of subunits including hexameric and pentameric proteins...
10.
Sutter M, Wilson S, Deutsch S, Kerfeld C
Photosynth Res
. 2013 Aug;
118(1-2):9-16.
PMID: 23949415
Cyanobacteria have evolved a unique carbon fixation organelle known as the carboxysome that compartmentalizes the enzymes RuBisCO and carbonic anhydrase. This effectively increases the local CO2 concentration at the active...