Steven Broadbent
Overview
Explore the profile of Steven Broadbent including associated specialties, affiliations and a list of published articles.
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5
Citations
109
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Recent Articles
1.
Lickiss B, Hunker J, Bhagwan J, Linder P, Thomas U, Lotay H, et al.
J Pharmacol Toxicol Methods
. 2024 Jun;
128:107529.
PMID: 38857637
Human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes (CMs) have found utility for conducting in vitro drug screening and disease modelling to gain crucial insights into pharmacology or disease phenotype. However,...
2.
Krashia P, Moroni M, Broadbent S, Hofmann G, Kracun S, Beato M, et al.
PLoS One
. 2010 Nov;
5(10):e13611.
PMID: 21049012
Background: The neuronal nicotinic receptors that mediate excitatory transmission in autonomic ganglia are thought to be formed mainly by the α3 and β4 subunits. Expressing this composition in oocytes fails...
3.
Broadbent S, Groot-Kormelink P, Krashia P, Harkness P, Millar N, Beato M, et al.
Mol Pharmacol
. 2006 Jul;
70(4):1350-7.
PMID: 16822928
The beta3 neuronal nicotinic subunit is localized in dopaminergic areas of the central nervous system, in which many other neuronal nicotinic subunits are expressed. So far, beta3 has only been...
4.
Groot-Kormelink P, Broadbent S, Beato M, Sivilotti L
Mol Pharmacol
. 2005 Nov;
69(2):558-63.
PMID: 16269534
Much of our understanding of ligand-gated ion channels comes from heterologous expression studies. However, this technique cannot produce receptors with a predetermined subunit composition for channels formed by several different...
5.
Shotton H, Broadbent S, Lincoln J
Auton Neurosci
. 2004 Apr;
111(1):57-65.
PMID: 15109939
Treatment with alpha-lipoic acid (LA) or evening primrose oil (EPO), individually, fails to prevent diabetes-induced changes in enteric nerves. Since synergy between these treatments has been reported, the aim was...