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Steven A Niederer

Explore the profile of Steven A Niederer including associated specialties, affiliations and a list of published articles. Areas
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Articles 140
Citations 2047
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Recent Articles
1.
de Vere F, Wijesuriya N, Howell S, Elliott M, Mehta V, Mannakkara N, et al.
Expert Rev Cardiovasc Ther . 2024 Dec; 1-18. PMID: 39695920
Introduction: Cardiac Resynchronization Therapy (CRT) is an effective treatment for heart failure (HF) in approximately two-thirds of recipients, with a third remaining CRT 'non-responders.' There is an increasing body of...
2.
Isbister J, Strocchi M, Riedy M, Yeates L, Gray B, Singer E, et al.
Heart Rhythm . 2024 Dec; PMID: 39675648
Background: Hydroquinidine reduces arrhythmic events in patients with Brugada syndrome (BrS). The mechanism by which it exerts antiarrhythmic benefit and its electrophysiological effects on BrS substrate remain incompletely understood. Objective:...
3.
Wijesuriya N, Strocchi M, Elliott M, Mehta V, de Vere F, Howell S, et al.
Heart Rhythm O2 . 2024 Sep; 5(8):551-560. PMID: 39263609
Background: Leadless cardiac resynchronization therapy (CRT) is an emerging heart failure treatment. An implanted electrode delivers lateral or septal endocardial left ventricular (LV) pacing (LVP) upon detection of a right...
4.
Wijesuriya N, de Vere F, Howell S, Mannakkara N, Bosco P, Frigiola A, et al.
Heart Rhythm . 2024 Sep; 22(2):546-553. PMID: 39260666
No abstract available.
5.
Wijesuriya N, Mehta V, de Vere F, Howell S, Mannakkara N, Sidhu B, et al.
Heart Rhythm . 2024 Aug; 22(2):357-364. PMID: 39209224
Background: Leadless left ventricular (LV) endocardial pacing is an emerging cardiac resynchronization therapy (CRT) technology. Predictors of response to leadless CRT are poorly understood. Implanting the LV endocardial pacing electrode...
6.
Dharmaprani D, Tiver K, Shahrbabaki S, Jenkins E, Chapman D, Strong C, et al.
Circ Arrhythm Electrophysiol . 2024 Jun; 17(7):e012684. PMID: 38939983
Background: Atrial fibrillation (AF) and ventricular fibrillation (VF) episodes exhibit varying durations, with some spontaneously ending quickly while others persist. A quantitative framework to explain episode durations remains elusive. We...
7.
Wijesuriya N, Mehta V, de Vere F, Howell S, Niederer S, Burri H, et al.
J Am Heart Assoc . 2024 Jun; 13(12):e035279. PMID: 38879456
Background: Studies have reported that female sex predicts superior cardiac resynchronization therapy (CRT) response. One theory is that this association is related to smaller female heart size, thus increased relative...
8.
Lewalle A, Milburn G, Campbell K, Niederer S
Biophys J . 2024 May; 123(18):2996-3009. PMID: 38807364
The length-dependent activation (LDA) of maximum force and calcium sensitivity are established features of cardiac muscle contraction but the dominant underlying mechanisms remain to be fully clarified. Alongside the well-documented...
9.
Muffoletto M, Xu H, Burns R, Suinesiaputra A, Nasopoulou A, Kunze K, et al.
Eur Heart J Cardiovasc Imaging . 2024 May; 25(10):1374-1383. PMID: 38723059
Aims: Standard methods of heart chamber volume estimation in cardiovascular magnetic resonance (CMR) typically utilize simple geometric formulae based on a limited number of slices. We aimed to evaluate whether...
10.
Salvador M, Strocchi M, Regazzoni F, Augustin C, Dede L, Niederer S, et al.
NPJ Digit Med . 2024 Apr; 7(1):90. PMID: 38605089
Cardiac digital twins provide a physics and physiology informed framework to deliver personalized medicine. However, high-fidelity multi-scale cardiac models remain a barrier to adoption due to their extensive computational costs....