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Steven A Frank

Explore the profile of Steven A Frank including associated specialties, affiliations and a list of published articles. Areas
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Articles 82
Citations 1276
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Recent Articles
1.
Frank S
Evolution . 2025 Mar; PMID: 40065655
Natural selection acts on traits at different scales, often with opposing consequences. This article identifies the particular forces that act at each scale and how those forces combine to determine...
2.
Frank S
Evol Lett . 2024 Sep; 8(5):719-725. PMID: 39328288
Organisms gain by anticipating future changes in the environment. Those environmental changes often follow stochastic trends. The steeper the slope of the trend, the more likely the trend's momentum carries...
3.
Frank S
Proc Natl Acad Sci U S A . 2024 Sep; 121(40):e2417410121. PMID: 39298476
No abstract available.
4.
Frank S, Yanai I
Trends Cancer . 2024 Aug; 10(10):880-892. PMID: 39112299
The traditional view of cancer emphasizes a genes-first process. Novel cancer traits arise by genetic mutations that spread to drive phenotypic change. However, recent data support a phenotypes-first process in...
5.
Frank S
Cell Syst . 2023 Dec; 14(12):1015-1020. PMID: 38128480
When a system robustly corrects component-level errors, the direct pressure on component performance declines. Components become less reliable, maintain more genetic variability, or drift neutrally, creating new forms of complexity....
6.
Frank S
Evol Med Public Health . 2023 Oct; 11(1):348-352. PMID: 37868077
Danger requires a strong rapid response. Speedy triggers are prone to false signals. False alarms can be costly, requiring strong negative regulators to oppose the initial triggers. Strongly opposed forces...
7.
Frank S
Entropy (Basel) . 2023 Aug; 25(8). PMID: 37628192
Organisms perceive their environment and respond. The origin of perception-response traits presents a puzzle. Perception provides no value without response. Response requires perception. Recent advances in machine learning may provide...
8.
Kummerli R, Frank S
Trends Microbiol . 2023 Apr; 31(7):665-667. PMID: 37117073
Cellular heterogeneity in clonal bacterial populations is widespread. Division of labor and bet hedging are common adaptive explanations for the function of such heterogeneity. We suggest group-level phenotypes via shareable...
9.
Frank S
Ecol Evol . 2023 Mar; 13(3):e9895. PMID: 36950372
Many scientific problems focus on observed patterns of change or on how to design a system to achieve particular dynamics. Those problems often require fitting differential equation models to target...
10.
Frank S
F1000Res . 2023 Mar; 11:1254. PMID: 36845325
A growing population of cells accumulates mutations. A single mutation early in the growth process carries forward to all descendant cells, causing the final population to have a lot of...