Steve Rowley
Overview
Explore the profile of Steve Rowley including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
226
Followers
0
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Recent Articles
1.
Pacini C, Duncan E, Goncalves E, Gilbert J, Bhosle S, Horswell S, et al.
Cancer Cell
. 2024 Jan;
42(2):301-316.e9.
PMID: 38215750
Genetic screens in cancer cell lines inform gene function and drug discovery. More comprehensive screen datasets with multi-omics data are needed to enhance opportunities to functionally map genetic vulnerabilities. Here,...
2.
Jung J, Lee J, Dickson M, Schwartz G, Cesne A, Varga A, et al.
Nat Commun
. 2016 Sep;
7:12609.
PMID: 27576846
In tumours that harbour wild-type p53, p53 protein function is frequently disabled by the mouse double minute 2 protein (MDM2, or HDM2 in humans). Multiple HDM2 antagonists are currently in...
3.
Sparano J, Goldstein L, Childs B, Shak S, Brassard D, Badve S, et al.
Clin Cancer Res
. 2011 Sep;
17(22):7194-203.
PMID: 21933890
Purpose: To conduct an exploratory analysis of the relationship between gene expression and recurrence in patients with operable triple-negative breast cancer (TNBC) treated with adjuvant doxorubicin-containing chemotherapy. Experimental Design: RNA...
4.
Sparano J, Goldstein L, Childs B, Shak S, Brassard D, Badve S, et al.
Clin Cancer Res
. 2009 Dec;
15(24):7693-7700.
PMID: 19996222
PURPOSE: To perform an exploratory analysis of the relationship between gene expression and recurrence in operable hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-normal breast cancer patients treated...
5.
Goldstein L, Gray R, Badve S, Childs B, Yoshizawa C, Rowley S, et al.
J Clin Oncol
. 2008 Aug;
26(25):4063-71.
PMID: 18678838
Purpose: Adjuvant! is a standardized validated decision aid that projects outcomes in operable breast cancer based on classical clinicopathologic features and therapy. Genomic classifiers offer the potential to more accurately...
6.
Pradines J, Farutin V, Rowley S, Dancik V
J Comput Biol
. 2005 Mar;
12(2):113-28.
PMID: 15767772
We present an analytical framework to analyze lists of proteins with large undirected graphs representing their known functional relationships. We consider edge-count variables such as the number of interactions between...
7.
Pradines J, Rudolph-Owen L, Hunter J, Leroy P, Cary M, Coopersmith R, et al.
J Biopharm Stat
. 2004 Oct;
14(3):701-21.
PMID: 15468760
We present a new computational method for identifying regulated pathway components in transcript profiling (TP) experiments by evaluating transcriptional activity in the context of known biological pathways. We construct a...