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Steve M Holland

Explore the profile of Steve M Holland including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 365
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Recent Articles
1.
Freeman A, Gonzalez C, Yates B, Cole K, Little L, Flannelly E, et al.
J Allergy Clin Immunol . 2024 Sep; 155(1):176-187. PMID: 39233015
Background: DOCK8 deficiency is a primary immunodeficiency in which allogeneic hematopoietic cell transplantation (HCT) represents the only known cure. We tested the ability of a busulfan-based regimen to achieve reliable...
2.
Le Voyer T, Parent A, Liu X, Cederholm A, Gervais A, Rosain J, et al.
Nature . 2023 Nov; 623(7988):803-813. PMID: 37938781
Patients with autoimmune polyendocrinopathy syndrome type 1 (APS-1) caused by autosomal recessive AIRE deficiency produce autoantibodies that neutralize type I interferons (IFNs), conferring a predisposition to life-threatening COVID-19 pneumonia. Here...
3.
Korol C, Shallom S, Arora K, Boshoff H, Freeman A, King A, et al.
Virulence . 2020 Dec; 11(1):1656-1673. PMID: 33356838
: We characterized BCG isolates found in lung and brain samples from a previously vaccinated patient with IFNγR1 deficiency. The isolates collected displayed distinct genomic and phenotypic features consistent with...
4.
Burbelo P, Browne S, Holland S, Iadarola M, Alevizos I
Clin Transl Med . 2019 Jan; 8(1):1. PMID: 30604130
Background: Sjögren's syndrome (SS) is an autoimmune disease characterized by immune attack on the salivary and lacrimal glands. Given the known cytokine activation and type I interferon gene expression signature...
5.
Shah N, Freeman A, Su H, Cole K, Parta M, Moutsopoulos N, et al.
Biol Blood Marrow Transplant . 2017 Mar; 23(6):980-990. PMID: 28288951
Dedicator-of-cytokinesis 8 (DOCK8) deficiency, a primary immunodeficiency disease, can be reversed by allogeneic hematopoietic stem cell transplantation (HSCT); however, there are few reports describing the use of alternative donor sources...
6.
Schlums H, Jung M, Han H, Theorell J, Bigley V, Chiang S, et al.
Blood . 2017 Feb; 129(14):1927-1939. PMID: 28209719
Heterozygous mutation is associated with immunodeficiency, lymphedema, and myelodysplastic syndrome. Disease presentation is variable, often coinciding with loss of circulating dendritic cells, monocytes, B cells, and natural killer (NK) cells....
7.
Lipsky A, Farooqui M, Tian X, Martyr S, Cullinane A, Nghiem K, et al.
Haematologica . 2015 Oct; 100(12):1571-8. PMID: 26430171
Ibrutinib is associated with bleeding-related adverse events of grade ≤ 2 in severity, and infrequently with grade ≥ 3 events. To investigate the mechanisms of bleeding and identify patients at...
8.
Henriet S, Jans J, Simonetti E, Kwon-Chung K, Rijs A, Hermans P, et al.
J Infect Dis . 2013 Mar; 207(12):1932-9. PMID: 23482646
Invasive aspergillosis is a major threat to patients with chronic granulomatous disease (CGD). Fungal pathogenesis is the result of a diminished antifungal capacity and dysregulated inflammation. A deficient NADPH-oxidase complex...
9.
Booty M, Chae J, Masters S, Remmers E, Barham B, Le J, et al.
Arthritis Rheum . 2009 May; 60(6):1851-61. PMID: 19479870
Objective: Familial Mediterranean fever (FMF) has traditionally been considered an autosomal-recessive disease; however, it has been observed that a substantial number of patients with clinical FMF possess only 1 demonstrable...
10.
Haerynck F, Holland S, Rosenzweig S, Casanova J, Schelstraete P, De Baets F
J Pediatr . 2008 Oct; 153(5):721-2. PMID: 18940359
A girl with relapsing cervical lymphadenopathy due to Mycobacterium avium subsequently developed abdominal adenopathy and intestinal inflammation. 1 known (c.1623_1624delGCinsTT) and 1 novel mutation (c.65_68delCTGC of exon2) of the Interleukin-12...