Stephen T Smiley
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Explore the profile of Stephen T Smiley including associated specialties, affiliations and a list of published articles.
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41
Citations
1339
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Recent Articles
1.
Maciel Jr M, Amara R, Bar K, Crotty S, Deeks S, Duplessis C, et al.
NPJ Vaccines
. 2024 Mar;
9(1):61.
PMID: 38485736
No abstract available.
2.
Maciel Jr M, Amara R, Bar K, Crotty S, Deeks S, Duplessis C, et al.
NPJ Vaccines
. 2024 Feb;
9(1):39.
PMID: 38383616
No abstract available.
3.
Smiley S, Szaba F, Kummer L, Duso D, Lin J
Infect Immun
. 2019 Feb;
87(5).
PMID: 30804102
Plague is a rapidly lethal human disease caused by the bacterium This study demonstrated that the plasminogen activator Pla, a protease that promotes fibrin degradation, thwarts T cell-mediated defense against...
4.
Lefebvre J, Lorenzo E, Masters A, Hopkins J, Eaton S, Smiley S, et al.
Oncotarget
. 2016 May;
7(23):33581-94.
PMID: 27177221
Influenza and pneumonia are leading causes of death in elderly populations. With age, there is an increased inflammatory response and slower viral clearance during influenza infection which increases the risk...
5.
Bane Jr C, Ivanov I, Matafonov A, Boyd K, Cheng Q, Sherwood E, et al.
PLoS One
. 2016 Apr;
11(4):e0152968.
PMID: 27046148
Sepsis, a systemic inflammatory response to infection, is often accompanied by abnormalities of blood coagulation. Prior work with a mouse model of sepsis induced by cecal ligation and puncture (CLP)...
6.
Smiley S, Singh A, Read S, Sharma O, Finzi D, Lane C, et al.
Clin Infect Dis
. 2014 Oct;
60(2):292-7.
PMID: 25273081
Combination antiretroviral therapy can suppress human immunodeficiency virus (HIV) infection but cannot completely eradicate the virus. A major obstacle in the quest for a cure is the difficulty in targeting...
7.
Szaba F, Kummer L, Duso D, Koroleva E, Tumanov A, Cooper A, et al.
PLoS Pathog
. 2014 May;
10(5):e1004142.
PMID: 24854422
Septic pneumonias resulting from bacterial infections of the lung are a leading cause of human death worldwide. Little is known about the capacity of CD8 T cell-mediated immunity to combat...
8.
Hickey A, Lin J, Kummer L, Szaba F, Duso D, Tighe M, et al.
Infect Immun
. 2013 Apr;
81(6):2123-32.
PMID: 23545300
Immunomodulatory agents potentially represent a new class of broad-spectrum antimicrobials. Here, we demonstrate that prophylaxis with immunomodulatory cytosine-phosphate-guanidine (CpG) oligodeoxynucleotide (ODN), a toll-like receptor 9 (TLR9) agonist, confers protection against...
9.
Luo D, Lin J, Parent M, Mullarky-Kanevsky I, Szaba F, Kummer L, et al.
J Immunol
. 2013 Mar;
190(8):4149-61.
PMID: 23487423
The Gram-negative bacterium Yersinia pestis causes plague, a rapidly progressing and often fatal disease. The formation of fibrin at sites of Y. pestis infection supports innate host defense against plague,...
10.
Freeman M, Burkum C, Lanzer K, Roberts A, Pinkevych M, Itakura A, et al.
J Autoimmun
. 2012 Dec;
42:71-9.
PMID: 23245703
Human herpesviruses establish lifelong latency. Viral recrudescence can lead to the development of cancers, immunoproliferative disorders, transplantation complications, and thrombocytopenia. Although platelet-specific autoantibodies have been reported in patients infected with...