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Stephen R Large

Explore the profile of Stephen R Large including associated specialties, affiliations and a list of published articles. Areas
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Articles 63
Citations 617
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Recent Articles
11.
Messer S, Page A, Rushton S, Berman M, Tsui S, Catarino P, et al.
J Heart Lung Transplant . 2019 Jul; 38(8):872-874. PMID: 31353001
No abstract available.
12.
Niederberger P, Farine E, Raillard M, Dornbierer M, Freed D, Large S, et al.
Circ Heart Fail . 2019 Apr; 12(4):e005517. PMID: 30998395
Heart transplantation remains the preferred option for improving quality of life and survival for patients suffering from end-stage heart failure. Unfortunately, insufficient supply of cardiac grafts has become an obstacle....
13.
Page A, Messer S, Large S
Ann Cardiothorac Surg . 2018 Mar; 7(1):75-81. PMID: 29492385
Fifty years since the first successful human heart transplant from a non-heart beating donor, this concept of heart transplantation from donation after circulatory determined death (DCD) promises to be one...
14.
White C, Messer S, Large S, Conway J, Kim D, Kutsogiannis D, et al.
Front Cardiovasc Med . 2018 Mar; 5:8. PMID: 29487855
Cardiac transplantation has become limited by a critical shortage of suitable organs from brain-dead donors. Reports describing the successful clinical transplantation of hearts donated after circulatory death (DCD) have recently...
15.
Messer S, Page A, Axell R, Berman M, Hernandez-Sanchez J, Colah S, et al.
J Heart Lung Transplant . 2017 Nov; 36(12):1311-1318. PMID: 29173394
Background: The requirement for heart transplantation is increasing, vastly outgrowing the supply of hearts available from donation after brain death (DBD) donors. Transplanting hearts after donation after circulatory-determined death (DCD)...
16.
Axell R, Messer S, White P, McCabe C, Priest A, Statopoulou T, et al.
Physiol Rep . 2017 Apr; 5(7). PMID: 28373412
Chronic thromboembolic disease (CTED) is suboptimally defined by a mean pulmonary artery pressure (mPAP) <25 mmHg at rest in patients that remain symptomatic from chronic pulmonary artery thrombi. To improve...
17.
Messer S, Axell R, Colah S, White P, Ryan M, Page A, et al.
J Heart Lung Transplant . 2016 Dec; 35(12):1443-1452. PMID: 27916176
Background: After a severe shortage of brain-dead donors, the demand for heart transplantation has never been greater. In an attempt to increase organ supply, abdominal and lung transplant programs have...
18.
Sastry P, Hughes V, Hayes P, Vallabhaneni S, Sharples L, Thompson M, et al.
BMJ Open . 2015 Jun; 5(6):e008147. PMID: 26038360
Introduction: Chronic thoracic aortic aneurysm (CTAA) affecting the arch or descending aorta is an indolent but life-threatening condition with a rising prevalence as the UK population ages. Treatment may be...
19.
Ali A, Downey P, Singh G, Qi W, George I, Takayama H, et al.
J Transl Med . 2014 Feb; 12:37. PMID: 24507588
Background: We aim to develop a rat model of veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Methods: VA-ECMO was established in twelve Male Sprague-Dawley rats (250-350 g) through cannulation of the right...
20.
Large S, Nashef S
Heart Fail Clin . 2013 Sep; 9(4):533-9, ix. PMID: 24054484
Surgery to correct a structural heart valve problem can restore sinus rhythm in approximately one-fifth of patients with atrial fibrillation (AF), and the addition of a maze procedure will increase...