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Stephen R Large

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Articles 63
Citations 617
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Recent Articles
1.
Sharples L, Anagnostopoulou V, Pouncey A, Freeman C, McCarthy A, Gray J, et al.
Br J Surg . 2024 Sep; 111(9). PMID: 39258491
Background: Surgical intervention for thoracic aortic aneurysms is high risk. Understanding changes in health-related quality of life before and after endovascular stent grafting and open surgical repair can aid treatment...
2.
Pouncey A, Patel D, Freeman C, Sastry P, Bicknell C, Large S, et al.
Br J Surg . 2024 Aug; 111(8. PMID: 39090749
Background: Women with thoracic aortic aneurysms within the arch or descending thoracic aorta have poorer survival than men. Sex differences in relative thoracic aortic aneurysm size may account for some...
3.
Arnold M, Do P, Davidson S, Large S, Helmer A, Beer G, et al.
Int J Mol Sci . 2024 Apr; 25(8). PMID: 38673737
Heart transplantation with donation after circulatory death (DCD) provides excellent patient outcomes and increases donor heart availability. However, unlike conventional grafts obtained through donation after brain death, DCD cardiac grafts...
4.
Cernic S, Page A, Messer S, Bhagra S, Pettit S, Dawson S, et al.
J Heart Lung Transplant . 2022 Jul; 41(9):1294-1302. PMID: 35811221
Background: Ex-situ heart perfusion (ESHP) is commonly used for the reanimation and preservation of hearts following donation after circulatory determined death (DCD). The only commercially available existing ESHP device promotes...
5.
Laurence C, Nachum E, Henwood S, Berman M, Large S, Messer S, et al.
J Heart Lung Transplant . 2022 May; 41(8):1104-1113. PMID: 35641424
Background: Limited availability of suitable donor hearts remains a challenge to pediatric heart transplantation, contributing to waitlist mortality. Controlled donation after circulatory death (DCD) has demonstrated success in adults. Early...
6.
Peled Y, Messer S, Large S, Kittleson M
J Heart Lung Transplant . 2021 Aug; 40(11):1419-1421. PMID: 34429239
No abstract available.
7.
Kondori J, Ghafouri R, Zamanzadeh V, Mirza Aghazadeh Attari A, Large S, Sheikhalipour Z
BMC Emerg Med . 2021 Aug; 21(1):91. PMID: 34344300
Background: Adverse attitudes and insufficient knowledge about organ donation after Circulatory Determined Death (DCD) among emergency staff can have important consequences for the proper identification of potential DCD donors. This...
8.
Messer S, Cernic S, Page A, Berman M, Kaul P, Colah S, et al.
J Heart Lung Transplant . 2020 Nov; 39(12):1463-1475. PMID: 33248525
Background: In an effort to address the increasing demand for heart transplantation within the United Kingdom (UK), we established a clinical program of heart transplantation from donation after circulatory-determined death...
9.
Karunanantham J, Ali J, Evans N, Webb S, Large S
J Card Surg . 2020 Oct; 35(11):3010-3016. PMID: 33111446
Background: Stroke remains a devastating complication of cardiac surgery. The aim of this study was to characterize the incidence of stroke and analyze the impact of stroke on patient outcomes...
10.
Messer S, Abu-Omar Y, Large S, Berman M, Page A, Kaul P, et al.
J Heart Lung Transplant . 2020 Sep; 39(12):1366-1371. PMID: 32958407
Combined heart-lung transplantation is the optimal treatment option for many patients with end-stage heart failure and fixed severe pulmonary hypertension. It offers the only possibility of long-term survival and a...