Stephen R Doyle
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Explore the profile of Stephen R Doyle including associated specialties, affiliations and a list of published articles.
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52
Citations
707
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Recent Articles
1.
Wangwiwatsin A, Kulwong S, Phuyao C, Titapun A, Loilome W, Klanrit P, et al.
Wellcome Open Res
. 2025 Feb;
10:1.
PMID: 39949572
We present a genome assembly from a specimen of (liver fluke; Platyhelminthes; Trematoda; Opisthorchiida; Opisthorchiidae). The genome sequence has a total length of 627.20 megabases. Most of the assembly (97.89%)...
2.
McIntyre J, Morrison A, Maitland K, Berger D, Price D, Dougan S, et al.
PLoS Pathog
. 2025 Feb;
21(2):e1012820.
PMID: 39913358
The parasitic nematode Teladorsagia circumcincta is one of the most important pathogens of sheep and goats in temperate climates worldwide and can rapidly evolve resistance to drugs used to control...
3.
Goulding D, Tolley C, Mkandawire T, Doyle S, Hart E, Airs P, et al.
PLoS Pathog
. 2025 Jan;
21(1):e1012502.
PMID: 39869639
Whipworms (Trichuris spp) are ubiquitous parasites of humans and domestic and wild mammals that cause chronic disease, considerably impacting human and animal health. Egg hatching is a critical phase in...
4.
Buddenborg S, Doyle S
Trends Parasitol
. 2024 Dec;
41(1):19-21.
PMID: 39638657
Reconciling organism-scale biology at cellular-scale resolution has been a monumental challenge. Recently, Gramberg et al. uncovered the spatial organisation of gene expression in the common liver fluke, Fasciola hepatica. These...
5.
Gandasegui J, Grau-Pujol B, Novela V, Muchisse O, Cambra-Pelleja M, Cossa A, et al.
Int J Parasitol Drugs Drug Resist
. 2024 Nov;
26:100570.
PMID: 39546832
Concerns about the emergence of benzimidazole resistance in soil-transmitted helminths (STH) infections, particularly against Trichuris trichiura, have arisen. Previous studies of veterinary nematodes have linked benzimidazole resistance to single-nucleotide polymorphisms...
6.
Extensive transmission and variation in a functional receptor for praziquantel resistance in endemic
Berger D, Park S, Crellen T, Vianney T, Kabatereine N, Cotton J, et al.
bioRxiv
. 2024 Sep;
PMID: 39257780
Mass-drug administration (MDA) of human populations using praziquantel monotherapy has become the primary strategy for controlling and potentially eliminating the major neglected tropical disease schistosomiasis. To understand how long-term MDA...
7.
Attenborough T, Rawlinson K, Diaz Soria C, Ambridge K, Sankaranarayanan G, Graham J, et al.
Elife
. 2024 Aug;
13.
PMID: 39190022
is a parasitic flatworm that causes the major neglected tropical disease schistosomiasis. The miracidium is the first larval stage of the life cycle. It swims and infects a freshwater snail,...
8.
Power R, Doyle S, Slapeta J
Exp Parasitol
. 2024 Jul;
263-264:108806.
PMID: 39009178
Dirofilaria immitis is a filarial parasitic nematode of veterinary significance. With the emergence of drug-resistant isolates in the USA, it is imperative to determine the likelihood of resistance occurring in...
9.
Antonopoulos A, Charvet C, Maitland K, Doyle S, Neveu C, Laing R
Int J Parasitol Drugs Drug Resist
. 2024 Feb;
24:100524.
PMID: 38346379
Recently, a S168T variant in the acetylcholine receptor subunit ACR-8 was associated with levamisole resistance in the parasitic helminth Haemonchus contortus. Here, we used the Xenopus laevis oocyte expression system...
10.
Antonopoulos A, Higgins O, Doyle S, Bartley D, Morrison A, Shalaby M, et al.
Mol Cell Probes
. 2023 Dec;
73:101946.
PMID: 38097144
Haemonchus contortus is a parasitic haematophagous nematode that primarily affects small ruminants and causes significant economic loss to the global livestock industry. Treatment of haemonchosis typically relies on broad-spectrum anthelmintics,...