Nancy Holroyd
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Explore the profile of Nancy Holroyd including associated specialties, affiliations and a list of published articles.
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56
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5157
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Recent Articles
1.
McIntyre J, Morrison A, Maitland K, Berger D, Price D, Dougan S, et al.
PLoS Pathog
. 2025 Feb;
21(2):e1012820.
PMID: 39913358
The parasitic nematode Teladorsagia circumcincta is one of the most important pathogens of sheep and goats in temperate climates worldwide and can rapidly evolve resistance to drugs used to control...
2.
Moescheid M, Lu Z, Soria C, Quack T, Puckelwaldt O, Holroyd N, et al.
Nucleic Acids Res
. 2024 Dec;
53(4).
PMID: 39676663
Studies on transcription regulation in platyhelminth development are scarce, especially for parasitic flatworms. Here, we employed single-cell transcriptomics to identify genes involved in reproductive development in the trematode model Schistosoma...
3.
Herz M, Zarowiecki M, Wessels L, Patzel K, Herrmann R, Braun C, et al.
Front Cell Infect Microbiol
. 2024 Feb;
14:1335946.
PMID: 38333034
The lethal zoonosis alveolar echinococcosis is caused by tumour-like growth of the metacestode stage of the tapeworm within host organs. We previously demonstrated that metacestode proliferation is exclusively driven by...
4.
Cole R, Holroyd N, Tracey A, Berriman M, Viney M
Nat Commun
. 2023 Oct;
14(1):6427.
PMID: 37833369
Nematodes are important parasites of people and animals, and in natural ecosystems they are a major ecological force. Strongyloides ratti is a common parasitic nematode of wild rats and we...
5.
Coghlan A, Partridge F, Duque-Correa M, Rinaldi G, Clare S, Seymour L, et al.
PLoS Negl Trop Dis
. 2023 Sep;
17(9):e0011205.
PMID: 37669291
Hundreds of millions of people worldwide are infected with the whipworm Trichuris trichiura. Novel treatments are urgently needed as current drugs, such as albendazole, have relatively low efficacy. We have...
6.
Dicks J, Fazal M, Oliver K, Grayson N, Turnbull J, Bane E, et al.
Microb Genom
. 2023 May;
9(5).
PMID: 37194944
The National Collection of Type Cultures (NCTC) was founded on 1 January 1920 in order to fulfil a recognized need for a centralized repository for bacterial and fungal strains within...
7.
Doyle S, Laing R, Bartley D, Morrison A, Holroyd N, Maitland K, et al.
Cell Rep
. 2022 Oct;
41(3):111522.
PMID: 36261007
Like other pathogens, parasitic helminths can rapidly evolve resistance to drug treatment. Understanding the genetic basis of anthelmintic drug resistance in parasitic nematodes is key to tracking its spread and...
8.
Vianney T, Berger D, Doyle S, Sankaranarayanan G, Serubanja J, Nakawungu P, et al.
PLoS Negl Trop Dis
. 2022 Aug;
16(8):e0010188.
PMID: 35981002
Populations within schistosomiasis control areas, especially those in Africa, are recommended to receive regular mass drug administration (MDA) with praziquantel (PZQ) as the main strategy for controlling the disease. The...
9.
Duque-Correa M, Goulding D, Rodgers F, Gillis J, Cormie C, Rawlinson K, et al.
Nat Commun
. 2022 Apr;
13(1):1725.
PMID: 35365634
Whipworms are large metazoan parasites that inhabit multi-intracellular epithelial tunnels in the large intestine of their hosts, causing chronic disease in humans and other mammals. How first-stage larvae invade host...
10.
Kincaid-Smith J, Tracey A, Augusto R, Bulla I, Holroyd N, Rognon A, et al.
PLoS Negl Trop Dis
. 2021 Dec;
15(12):e0010062.
PMID: 34941866
Schistosomes cause schistosomiasis, the world's second most important parasitic disease after malaria in terms of public health and social-economic impacts. A peculiar feature of these dioecious parasites is their ability...