Stephen Oakeshott
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Explore the profile of Stephen Oakeshott including associated specialties, affiliations and a list of published articles.
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9
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168
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Recent Articles
1.
Curtin P, Farrar A, Oakeshott S, Sutphen J, Berger J, Mazzella M, et al.
Front Behav Neurosci
. 2016 Jan;
9:361.
PMID: 26793080
Huntington's Disease (HD) is a progressive neurodegenerative disorder that causes motor, cognitive, and psychiatric symptoms. In these experiments, we tested if operant training at an early age affected adult cognitive...
2.
Oakeshott S, Port R, Cummins-Sutphen J, Berger J, Watson-Johnson J, Ramboz S, et al.
PLoS Curr
. 2015 Dec;
4:e4f972cffe82c0.
PMID: 23925262
Apathy, characterized by generally reduced interest in and likelihood to perform goal-directed actions, is a recognized symptom of Huntington's disease (HD), a devastating neurological disorder caused by a CAG repeat...
3.
Farrar A, Murphy C, Paterson N, Oakeshott S, He D, Alosio W, et al.
J Huntingtons Dis
. 2014 Jul;
3(2):145-58.
PMID: 25062858
Background: Huntington's disease (HD) is characterized not only by severe motor deficits but also by early cognitive dysfunction that significantly increases the burden of the disease for patients and caregivers....
4.
Deficits in a Simple Visual Go/No-go Discrimination Task in Two Mouse Models of Huntington's Disease
Oakeshott S, Farrar A, Port R, Cummins-Sutphen J, Berger J, Watson-Johnson J, et al.
PLoS Curr
. 2013 Nov;
5.
PMID: 24270512
Huntington's disease (HD), a devastating neurodegenerative disorder caused by a CAG repeat expansion on the HTT gene located on chromosome 4, is associated with a characteristic pattern of progressive cognitive...
5.
Kudwa A, Menalled L, Oakeshott S, Murphy C, Mushlin R, Fitzpatrick J, et al.
PLoS Curr
. 2013 Sep;
5.
PMID: 24042107
The genome of the Bacterial Artificial Chromosome (BAC) transgenic mouse model of Huntington's Disease (BAC HD) contains the 170 kb human HTT locus modified by the addition of exon 1...
6.
Balci F, Oakeshott S, Shamy J, El-Khodor B, Filippov I, Mushlin R, et al.
PLoS Curr
. 2013 Jul;
5.
PMID: 23863947
Phenotyping with traditional behavioral assays constitutes a major bottleneck in the primary screening, characterization, and validation of genetic mouse models of disease, leading to downstream delays in drug discovery efforts....
7.
Oakeshott S, Port R, Cummins-Sutphen J, Watson-Johnson J, Ramboz S, Park L, et al.
PLoS Curr
. 2012 Apr;
3:RRN1282.
PMID: 22512000
Mouse models of Huntington's disease (HD) were trained to acquire one of two simple instrumental responses (a lever press or a nosepoke) to obtain food reinforcement. Animals from several HD...
8.
Oakeshott S, Balci F, Filippov I, Murphy C, Port R, Connor D, et al.
PLoS Curr
. 2011 Apr;
3:RRN1225.
PMID: 21479110
Huntington's disease (HD) is a progressive neurodegenerative disease marked by psychiatric and motor problems. Recently, these findings have been extended to deficits in sleep and circadian function that can be...
9.
Delamater A, Oakeshott S
Ann N Y Acad Sci
. 2007 Mar;
1104:1-20.
PMID: 17344542
The nature of the reward representation in Pavlovian conditioning has been of perennial interest to students of associative learning theory. We consider the view that it consists of a range...