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Stephen K Kaptoge

Explore the profile of Stephen K Kaptoge including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 877
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Recent Articles
1.
Gaziano L, Sun L, Arnold M, Bell S, Cho K, Kaptoge S, et al.
Circulation . 2022 Oct; 146(20):1507-1517. PMID: 36314129
Background: End-stage renal disease is associated with a high risk of cardiovascular events. It is unknown, however, whether mild-to-moderate kidney dysfunction is causally related to coronary heart disease (CHD) and...
2.
Poole K, Chappell D, Clark E, Fleming J, Shepstone L, Turmezei T, et al.
BMJ Open . 2022 May; 12(5):e050343. PMID: 35613783
Introduction: Two million out of the UK's 5 million routine diagnostic CT scans performed each year incorporate the thoracolumbar spine or pelvic region. Up to one-third reveal undiagnosed osteoporosis or...
3.
Ahmed S, Reithinger R, Kaptoge S, Ngondi J
Am J Trop Med Hyg . 2020 Aug; 103(4):1380-1387. PMID: 32815497
By sustaining transmission or causing malaria outbreaks, imported malaria undermines malaria elimination efforts. Few studies have examined the impact of travel on malaria epidemiology. We conducted a literature review and...
4.
Sun Y, Burgess S, Staley J, Wood A, Bell S, Kaptoge S, et al.
BMJ . 2019 Apr; 364:l1042. PMID: 30957776
Editor's Note: Please see the Editor's Note (doi: https://doi.org/10.1136/bmj.l1042) on Methodological Criticism and an Updated Analysis Objective: To investigate the shape of the causal relation between body mass index (BMI)...
5.
Armbrecht G, Felsenberg D, Ganswindt M, Lunt M, Kaptoge S, Abendroth K, et al.
Rheumatology (Oxford) . 2017 Apr; 56(7):1189-1199. PMID: 28398504
Objectives: To assess the prevalences across Europe of radiological indices of degenerative inter-vertebral disc disease (DDD); and to quantify their associations with, age, sex, physical anthropometry, areal BMD (aBMD) and...
6.
Oei L, Estrada K, Duncan E, Christiansen C, Liu C, Langdahl B, et al.
Bone . 2014 Feb; 59:20-7. PMID: 24516880
Vertebral fracture risk is a heritable complex trait. The aim of this study was to identify genetic susceptibility factors for osteoporotic vertebral fractures applying a genome-wide association study (GWAS) approach....
7.
Moayyeri A, Hsu Y, Karasik D, Estrada K, Xiao S, Nielson C, et al.
Hum Mol Genet . 2014 Jan; 23(11):3054-68. PMID: 24430505
Quantitative ultrasound of the heel captures heel bone properties that independently predict fracture risk and, with bone mineral density (BMD) assessed by X-ray (DXA), may be convenient alternatives for evaluating...
8.
Oei L, Hsu Y, Styrkarsdottir U, Eussen B, de Klein A, Peters M, et al.
J Med Genet . 2013 Dec; 51(2):122-31. PMID: 24343915
Background: Osteoporosis is a systemic skeletal disease characterised by reduced bone mineral density and increased susceptibility to fracture; these traits are highly heritable. Both common and rare copy number variants...
9.
Estrada K, Styrkarsdottir U, Evangelou E, Hsu Y, Duncan E, Ntzani E, et al.
Nat Genet . 2012 Apr; 44(5):491-501. PMID: 22504420
Bone mineral density (BMD) is the most widely used predictor of fracture risk. We performed the largest meta-analysis to date on lumbar spine and femoral neck BMD, including 17 genome-wide...