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Stephen J Wicks

Explore the profile of Stephen J Wicks including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 318
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Recent Articles
1.
Wiley L, Shortt J, Roberts E, Lowery J, Kudron E, Lin M, et al.
Am J Hum Genet . 2024 Jan; 111(1):11-23. PMID: 38181729
Precision medicine initiatives across the globe have led to a revolution of repositories linking large-scale genomic data with electronic health records, enabling genomic analyses across the entire phenome. Many of...
2.
Zhou W, Kanai M, Wu K, Rasheed H, Tsuo K, Hirbo J, et al.
Cell Genom . 2023 Feb; 2(10):100192. PMID: 36777996
Biobanks facilitate genome-wide association studies (GWASs), which have mapped genomic loci across a range of human diseases and traits. However, most biobanks are primarily composed of individuals of European ancestry....
3.
Konigsberg I, Barnes B, Campbell M, Davidson E, Zhen Y, Pallisard O, et al.
Commun Med (Lond) . 2023 Feb; 1(1):42. PMID: 36750622
Background: Since the onset of the SARS-CoV-2 pandemic, most clinical testing has focused on RT-PCR. Host epigenome manipulation post coronavirus infection suggests that DNA methylation signatures may differentiate patients with...
4.
Konigsberg I, Barnes B, Campbell M, Davidson E, Zhen Y, Pallisard O, et al.
Commun Med (Lond) . 2022 Jan; 1(1):42. PMID: 35072167
Background: Since the onset of the SARS-CoV-2 pandemic, most clinical testing has focused on RT-PCR. Host epigenome manipulation post coronavirus infection suggests that DNA methylation signatures may differentiate patients with...
5.
Schmanski A, Roberts E, Coors M, Wicks S, Arbet J, Weber R, et al.
J Genet Couns . 2020 Sep; 30(1):257-267. PMID: 32951257
The number of institutional and governmental biobanks and the target enrollment sizes of modern biobanks are increasing, affording more opportunities for the public to participate in biobanking efforts. In parallel...
6.
Saben J, Shelton S, Hopkinson A, Sonn B, Mills E, Welham M, et al.
Acad Emerg Med . 2018 Sep; 26(6):639-647. PMID: 30239069
The Emergency Medicine Specimen Bank (EMSB) was developed to facilitate precision medicine in acute care. The EMSB is a biorepository of clinical health data and biospecimens collected from all adult...
7.
Wicks S, Haros K, Maillard M, Song L, Cohen R, Ten Dijke P, et al.
Oncogene . 2005 Jul; 24(54):8080-4. PMID: 16027725
Disruption of components in the transforming growth factor-beta (TGF-beta) signalling cascade is a common occurrence in human cancers. TGF-beta pathway activation is accomplished via serine/threonine kinase receptors and intracellular Smad...
8.
Wicks S, Mason R, Chantry A
Biochem J . 2002 Mar; 362(Pt 3):643-9. PMID: 11879191
Transforming growth factor-beta (TGFbeta) is a key mediator of extracellular matrix (ECM) accumulation in sclerotic kidney diseases such as diabetic nephropathy. One of the main target cells for TGFbeta in...