Stephen J Valentine
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Explore the profile of Stephen J Valentine including associated specialties, affiliations and a list of published articles.
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92
Citations
1584
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Recent Articles
1.
Sharif D, Dewasurendra V, Sultana M, Mahmud S, Banerjee C, Rahman M, et al.
J Phys Chem B
. 2025 Jan;
129(5):1626-1639.
PMID: 39878076
Capillary vibrating sharp-edge spray ionization (cVSSI) has been used to control the droplet charging of nebulized microdroplets and monitor effects on protein ion conformation makeup as determined by mass spectrometry...
2.
Rahman M, Sultana M, Sharif D, Mahmud S, Legleiter J, Li P, et al.
ACS Phys Chem Au
. 2025 Jan;
5(1):17-29.
PMID: 39867440
In-droplet hydrogen/deuterium exchange (HDX)-mass spectrometry (MS) experiments have been conducted for peptides of highly varied conformational type. A new model is presented that combines the use of protection factors (PF)...
3.
Wang J, Xue B, Awoyemi O, Yuliantoro H, Mendis L, DeVor A, et al.
Anal Chim Acta
. 2024 Oct;
1329:343241.
PMID: 39396304
Background: Single cell mass spectrometry (scMS) has shown great promise for label free proteomics analysis recently. To present single cell samples for proteomics analysis by MS is not a trivial...
4.
Attanayake K, Mahmud S, Banerjee C, Sharif D, Rahman M, Majuta S, et al.
Int J Mass Spectrom
. 2024 Jun;
499.
PMID: 38854816
Capillary vibrating sharp-edge spray ionization (cVSSI) combined with hydrogen/deuterium exchange-mass spectrometry (HDX-MS) has been utilized to characterize different solution-phase DNA conformers including DNA G-quadruplex topologies as well as triplex DNA...
5.
Jung J, Ewing M, Valentine S, Clemmer D
J Am Soc Mass Spectrom
. 2024 Apr;
35(5):982-991.
PMID: 38597281
The structural characterization and differentiation of four types of oligoubiquitin conjugates [linear (Met1)-, Lys11-, Lys48-, Lys63-linked di-, tri-, and tetraubiquitin chains] using ion mobility mass spectrometry are reported. A comparison...
6.
Kunovac A, Hathaway Q, Thapa D, Durr A, Taylor A, Rizwan S, et al.
Nanotoxicology
. 2024 Jan;
17(10):651-668.
PMID: 38180356
N-methyladenosine (mA) is the most prominent epitranscriptomic modification to RNA in eukaryotes, but it's role in adaptive changes within the gestational environment are poorly understood. We propose that gestational exposure...
7.
Stonebraker A, Hankin R, Kapp K, Li P, Valentine S, Legleiter J
Biophys Chem
. 2023 Oct;
303:107123.
PMID: 37852163
Toxic aggregation of pathogenic huntingtin protein (htt) is implicated in Huntington's disease and influenced by various factors, including the first seventeen amino acids at the N-terminus (Nt17) and the presence...
8.
Wang J, Curtin K, Valentine S, Li P
Anal Chim Acta
. 2023 Oct;
1279:341792.
PMID: 37827686
Combining microfluidics with mass spectrometry (MS) analysis has great potential for enabling new analytical applications and simplifying existing MS workflows. The rapid development of 3D printing technology has enabled direct...
9.
Sharif D, Rahman M, Mahmud S, Sultana M, Attanayake K, DeBastiani A, et al.
Rapid Commun Mass Spectrom
. 2023 Jul;
37(16):e9593.
PMID: 37430450
Rationale: Many different structure analysis techniques are not capable of probing the heterogeneity of solution conformations. Here, we examine the ability of in-droplet hydrogen-deuterium exchange (HDX) to directly probe solution...
10.
Stonebraker A, Beasley M, Massinople S, Wunder M, Li P, Valentine S, et al.
Protein Sci
. 2023 Apr;
32(5):e4642.
PMID: 37052951
Huntington's disease (HD) is a neurodegenerative disease resulting from an expansion of the polyglutamine (polyQ) domain within the huntingtin protein (htt). PolyQ expansion triggers toxic aggregation and alters htt/lipid interactions....