Stephen J Tam
Overview
Explore the profile of Stephen J Tam including associated specialties, affiliations and a list of published articles.
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5
Citations
237
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Recent Articles
1.
Renz M, Torres R, Dolan P, Tam S, Tapia J, Li L, et al.
Amyloid
. 2016 Aug;
23(3):168-177.
PMID: 27494229
Amyloid light chain (AL) amyloidosis is characterized by misfolded light chain (LC) (amyloid) deposition in various peripheral organs, leading to progressive dysfunction and death. There are no regulatory agency-approved treatments...
2.
Higaki J, Chakrabartty A, Galant N, Hadley K, Hammerson B, Nijjar T, et al.
Amyloid
. 2016 Mar;
23(2):86-97.
PMID: 26981744
Introduction: Transthyretin amyloidosis (ATTR amyloidosis) is caused by the misfolding and deposition of the transthyretin (TTR) protein and results in progressive multi-organ dysfunction. TTR epitopes exposed by dissociation and misfolding...
3.
Chen M, Maloney J, Kallop D, Atwal J, Tam S, Baer K, et al.
J Neurosci
. 2012 Sep;
32(39):13439-53.
PMID: 23015435
In addition to being a hallmark of neurodegenerative disease, axon degeneration is used during development of the nervous system to prune unwanted connections. In development, axon degeneration is tightly regulated...
4.
Tam S, Richmond D, Kaminker J, Modrusan Z, Martin-McNulty B, Cao T, et al.
Dev Cell
. 2012 Feb;
22(2):403-17.
PMID: 22340501
Signaling events that regulate central nervous system (CNS) angiogenesis and blood-brain barrier (BBB) formation are only beginning to be elucidated. By evaluating the gene expression profile of mouse vasculature, we...
5.
Tam S, Watts R
Annu Rev Neurosci
. 2010 Apr;
33:379-408.
PMID: 20367445
The vascular and nervous systems share a common necessity of circuit formation to coordinate nutrient and information transfer, respectively. Shared developmental principles have evolved to orchestrate the formation of both...