Stephen J Streatfield
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Explore the profile of Stephen J Streatfield including associated specialties, affiliations and a list of published articles.
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58
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1556
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Recent Articles
1.
Wagner N, Musiychuk K, Shoji Y, Tottey S, Streatfield S, Fischer R, et al.
Biotechnol J
. 2024 May;
19(5):e2300715.
PMID: 38797727
Human erythropoietin (hEPO) is one of the most in-demand biopharmaceuticals, however, its production is challenging. When produced in a plant expression system, hEPO results in extensive plant tissue damage and...
2.
Tottey S, Shoji Y, Mark Jones R, Musiychuk K, Chichester J, Miura K, et al.
Vaccine
. 2022 Dec;
41(4):938-944.
PMID: 36585278
Malaria kills around 409,000 people a year, mostly children under the age of five. Malaria transmission-blocking vaccines work to reduce malaria prevalence in a community and have the potential to...
3.
Wang X, Prokhnevsky A, Skarjinskaia M, Razzak M, Streatfield S, Lee J
Plant Biotechnol J
. 2022 Dec;
21(3):635-645.
PMID: 36511837
Molecular farming technology using transiently transformed Nicotiana plants offers an economical approach to the pharmaceutical industry to produce an array of protein targets including vaccine antigens and therapeutics. It can...
4.
Ganesan P, Kulchar R, Kaznica P, Montoya-Lopez R, Green B, Streatfield S, et al.
Plant Biotechnol J
. 2022 Oct;
21(2):244-246.
PMID: 36314106
No abstract available.
5.
Volokhov D, Fry A, Furtak V, Mark Jones R, Musiychuk K, Norikane J, et al.
Mol Cell Probes
. 2022 Apr;
63:101815.
PMID: 35364264
The potency of human and veterinary rabies vaccines is measured based on the National Institute of Health (NIH) potency test that is laborious, time-consuming, variable, and requires sacrifice of large...
6.
Paolino K, Regules J, Moon J, Ruck R, Bennett J, Remich S, et al.
Vaccine
. 2022 Feb;
40(12):1864-1871.
PMID: 35153091
Background: The potential use of Bacillus anthracis as a bioterrorism weapon requires a safe and effective vaccine that can be immediately distributed for mass vaccination. Protective antigen (PA), a principal...
7.
Daniell H, Nair S, Esmaeili N, Wakade G, Shahid N, Ganesan P, et al.
Mol Ther
. 2021 Nov;
30(5):1966-1978.
PMID: 34774754
To advance a novel concept of debulking virus in the oral cavity, the primary site of viral replication, virus-trapping proteins CTB-ACE2 were expressed in chloroplasts and clinical-grade plant material was...
8.
Karczewski J, Brown C, Maezato Y, Krasucki S, Streatfield S
J Antimicrob Chemother
. 2021 Feb;
76(6):1532-1538.
PMID: 33582800
Objectives: To evaluate the efficacy of a novel lantibiotic, CMB001, against MRSA biofilms in vitro and in an in vivo experimental model of bacterial infection. Methods: Antibacterial activity of CMB001...
9.
Karczewski J, Krasucki S, Asare-Okai P, Diehl C, Friedman A, Brown C, et al.
Front Microbiol
. 2020 Dec;
11:598789.
PMID: 33324379
We have isolated and characterized a novel antibacterial peptide, CMB001, following an extensive screening effort of bacterial species isolated from diverse environmental sources. The bacterium that produces CMB001 is characterized...
10.
Herbert A, Froude J, Ortiz R, Kuehne A, Dorosky D, Bakken R, et al.
Proc Natl Acad Sci U S A
. 2020 Feb;
117(7):3768-3778.
PMID: 32015126
Antibody-based therapies are a promising treatment option for managing ebolavirus infections. Several Ebola virus (EBOV)-specific and, more recently, pan-ebolavirus antibody cocktails have been described. Here, we report the development and...