Stephen J Goodswen
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Explore the profile of Stephen J Goodswen including associated specialties, affiliations and a list of published articles.
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18
Citations
272
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Recent Articles
1.
Goodswen S, Kennedy P, Ellis J
Sci Rep
. 2023 May;
13(1):8243.
PMID: 37217589
Vaccine discovery against eukaryotic parasites is not trivial as highlighted by the limited number of known vaccines compared to the number of protozoal diseases that need one. Only three of...
2.
Goodswen S, Kennedy P, Ellis J
FEMS Microbiol Rev
. 2023 Feb;
47(2).
PMID: 36806618
Reverse vaccinology (RV) was described at its inception in 2000 as an in silico process that starts from the genomic sequence of the pathogen and ends with a list of...
3.
Goodswen S, Kennedy P, Ellis J
Sci Rep
. 2022 Jun;
12(1):10349.
PMID: 35725870
The World Health Organisation reported in 2020 that six of the top 10 sources of death in low-income countries are parasites. Parasites are microorganisms in a relationship with a larger...
4.
Goodswen S, Kennedy P, Ellis J
Front Genet
. 2021 Aug;
12:716132.
PMID: 34367264
Bovine babesiosis causes significant annual global economic loss in the beef and dairy cattle industry. It is a disease instigated from infection of red blood cells by haemoprotozoan parasites of...
5.
Goodswen S, Kennedy P, Ellis J
Pathogens
. 2021 Jun;
10(6).
PMID: 34071992
infection of red blood cells can cause a severe disease called babesiosis in susceptible hosts. Bovine babesiosis causes global economic loss to the beef and dairy cattle industries, and canine...
6.
Goodswen S, Barratt J, Kennedy P, Kaufer A, Calarco L, Ellis J
FEMS Microbiol Rev
. 2021 Mar;
45(5).
PMID: 33724378
To understand the intricacies of microorganisms at the molecular level requires making sense of copious volumes of data such that it may now be humanly impossible to detect insightful data...
7.
Goodswen S, Kennedy P, Ellis J
Methods Mol Biol
. 2020 Sep;
2183:29-42.
PMID: 32959239
Bioinformatics programs have been developed that exploit informative signals encoded within protein sequences to predict protein characteristics. Unfortunately, there is no program as yet that can predict whether a protein...
8.
Goodswen S, Kennedy P, Ellis J
Front Genet
. 2018 Sep;
9:332.
PMID: 30177953
Over the last two decades, various approaches have been developed and refined that attempt to identify protein and/or peptide vaccines candidates from informative signals encoded in protein sequences of a...
9.
Goodswen S, Kennedy P, Ellis J
Int J Parasitol
. 2017 Sep;
47(12):779-790.
PMID: 28893639
Reverse vaccinology has the potential to rapidly advance vaccine development against parasites, but it is unclear which features studied in silico will advance vaccine development. Here we consider Neospora caninum...
10.
Goodswen S, Barratt J, Kennedy P, Ellis J
Int J Parasitol
. 2015 Mar;
45(5):305-18.
PMID: 25747726
Neospora caninum is an apicomplexan parasite which can cause abortion in cattle, instigating major economic burden. Vaccination has been proposed as the most cost-effective control measure to alleviate this burden....