Stephen J Bush
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Explore the profile of Stephen J Bush including associated specialties, affiliations and a list of published articles.
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Articles
58
Citations
961
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Recent Articles
1.
Sun P, Bush S, Wang S, Jia P, Li M, Xu T, et al.
Cell Genom
. 2025 Feb;
5(2):100771.
PMID: 39947134
Analyzing spatial transcriptomics data from tumor tissues poses several challenges beyond those of healthy samples, including unclear boundaries between different regions, uneven cell densities, and relatively higher cellular heterogeneity. Collectively,...
2.
Xu D, Guo M, Xu X, Luo G, Liu Y, Bush S, et al.
Nat Microbiol
. 2025 Feb;
10(2):509-526.
PMID: 39901059
Human enteric α-defensin 5 (HD5) is an immune system peptide that acts as an important antimicrobial factor but is also known to promote pathogen infections by enhancing adhesion of the...
3.
Carter-Cusack D, Huang S, Keshvari S, Patkar O, Sehgal A, Allavena R, et al.
PLoS Genet
. 2025 Jan;
21(1):e1011525.
PMID: 39869647
Adaptation to existence outside the womb is a key event in the life of a mammal. The absence of macrophages in rats with a homozygous mutation in the colony-stimulating factor...
4.
Gao S, Zhang Y, Bush S, Wang B, Yang X, Ye K
Genomics Proteomics Bioinformatics
. 2024 Oct;
22(5).
PMID: 39423139
High-fidelity (HiFi) sequencing has facilitated the assembly and analysis of the most repetitive region of the genome, the centromere. Nevertheless, our current understanding of human centromeres is based on a...
5.
Meyer V, Bush S, Botes A, Kaur M
Front Genet
. 2024 Oct;
15:1497486.
PMID: 39403118
No abstract available.
6.
Bush S, Goriely A
Andrology
. 2024 Sep;
PMID: 39291969
Recent advances in single-cell transcriptomic data have greatly expanded our understanding of both spermatogenesis and the molecular mechanisms of male infertility. However, this growing wealth of data could also shed...
7.
Wood K, Tong R, Motta M, Cordeddu V, Scimone E, Bush S, et al.
Am J Hum Genet
. 2024 Aug;
111(9):1953-1969.
PMID: 39116879
While it is widely thought that de novo mutations (DNMs) occur randomly, we previously showed that some DNMs are enriched because they are positively selected in the testes of aging...
8.
Gao S, Jia Y, Guo H, Xu T, Wang B, Bush S, et al.
Cell Genom
. 2024 Jul;
4(8):100626.
PMID: 39084227
Understanding the roles played by centromeres in chromosome evolution and speciation is complicated by the fact that centromeres comprise large arrays of tandemly repeated satellite DNA, which hinders high-quality assembly....
9.
Bush S, Nikola R, Han S, Suzuki S, Yoshida S, Simons B, et al.
Cells
. 2024 May;
13(9).
PMID: 38727278
Spermatogenesis involves a complex process of cellular differentiation maintained by spermatogonial stem cells (SSCs). Being critical to male reproduction, it is generally assumed that spermatogenesis starts and ends in equivalent...
10.
Wang B, Jia Y, Dang N, Yu J, Bush S, Gao S, et al.
BMC Genomics
. 2024 Apr;
25(1):356.
PMID: 38600443
Background: Centromeres play a crucial and conserved role in cell division, although their composition and evolutionary history in green algae, the evolutionary ancestors of land plants, remains largely unknown. Results:...