Stephen I Lentz
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Explore the profile of Stephen I Lentz including associated specialties, affiliations and a list of published articles.
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36
Citations
922
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Recent Articles
1.
Kazyken D, Lentz S, Wadley M, Fingar D
J Biol Chem
. 2023 Jul;
299(9):105097.
PMID: 37507012
The conserved protein kinase mTOR (mechanistic target of rapamycin) responds to diverse environmental cues to control cell metabolism and promote cell growth, proliferation, and survival as part of two multiprotein...
2.
Elzinga S, Koubek E, Hayes J, Carter A, Mendelson F, Webber-Davis I, et al.
Front Cell Neurosci
. 2023 May;
17:1167688.
PMID: 37206668
Introduction: The prevalence of obesity, prediabetes, and diabetes continues to grow worldwide. These metabolic dysfunctions predispose individuals to neurodegenerative diseases and cognitive impairment, including dementias such as Alzheimer's disease and...
3.
Jeyarajan S, Zhang I, Arvan P, Lentz S, Satin L
Biosensors (Basel)
. 2023 Mar;
13(3).
PMID: 36979594
The free calcium (Ca) levels in pancreatic beta cell organelles have been the subject of many recent investigations. Under pathophysiological conditions, disturbances in these pools have been linked to altered...
4.
Elzinga S, Henn R, Murdock B, Kim B, Hayes J, Mendelson F, et al.
Front Immunol
. 2022 Oct;
13:1012594.
PMID: 36248795
Obesity, prediabetes, and diabetes are growing in prevalence worldwide. These metabolic disorders are associated with neurodegenerative diseases, particularly Alzheimer's disease and Alzheimer's disease related dementias. Innate inflammatory signaling plays a...
5.
Perkins B, Lovblom L, Lewis E, Bril V, Ferdousi M, Orszag A, et al.
Diabetes Care
. 2021 Jul;
44(9):2107-2114.
PMID: 34210657
Objective: Corneal nerve fiber length (CNFL) has been shown in research studies to identify diabetic peripheral neuropathy (DPN). In this longitudinal diagnostic study, we assessed the ability of CNFL to...
6.
Bragazzi Cunha J, Elenbaas J, Maitra D, Kuo N, Azuero-Dajud R, Ferguson A, et al.
Sci Rep
. 2021 May;
11(1):9601.
PMID: 33953217
Congenital erythropoietic porphyria (CEP) is a rare genetic disorder leading to accumulation of uro/coproporphyrin-I in tissues due to inhibition of uroporphyrinogen-III synthase. Clinical manifestations of CEP include bone fragility, severe...
7.
Losiewicz M, Elghazi L, Fingar D, Rajala R, Lentz S, Fort P, et al.
Exp Eye Res
. 2020 Jul;
197:108131.
PMID: 32622801
The retina is one of the most metabolically active tissues, yet the processes that control retinal metabolism remains poorly understood. The mTOR complex (mTORC) that drives protein and lipid biogenesis...
8.
Arias-Hervert E, Xu N, Njus M, Murphy G, Hou Y, Williams J, et al.
Physiol Rep
. 2020 May;
8(9):e14428.
PMID: 32358861
Members of the Rab3 gene family are considered central to membrane trafficking of synaptic vesicles at mammalian central excitatory synapses. Recent evidence, however, indicates that the Rab27B-GTPase, which is highly...
9.
Kollmer J, Hegenbart U, Kimmich C, Hund E, Purrucker J, Hayes J, et al.
Ann Clin Transl Neurol
. 2020 Apr;
7(5):799-807.
PMID: 32333729
Objective: To quantify peripheral nerve lesions in symptomatic and asymptomatic hereditary transthyretin amyloidosis with polyneuropathy (ATTRv-PNP) by analyzing the magnetization transfer ratio (MTR) of the sciatic nerve, and to test...
10.
Hooton J, Kim K, Lentz S, Hicks N, Jones K, McCoy K, et al.
Cornea
. 2019 May;
38(8):1023-1028.
PMID: 31090594
Purpose: The purpose of this study was to determine the safety of long-term storage and shipping of prestripped, prestained, and preloaded Descemet membrane endothelial keratoplasty (pDMEK) grafts. Methods: A total...