Stephen H Powis
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Explore the profile of Stephen H Powis including associated specialties, affiliations and a list of published articles.
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30
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815
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Recent Articles
1.
Whitty C, Smith G, McBride M, Atherton F, Powis S, Stokes-Lampard H
BMJ
. 2023 Feb;
380:201.
PMID: 36725004
No abstract available.
2.
3.
Sekula P, Li Y, Stanescu H, Wuttke M, Ekici A, Bockenhauer D, et al.
Nephrol Dial Transplant
. 2016 Jun;
32(2):325-332.
PMID: 27333618
Background: Membranous nephropathy (MN) is a common cause of nephrotic syndrome in adults. Previous genome-wide association studies (GWAS) of 300 000 genotyped variants identified MN-associated loci at HLA-DQA1 and PLA2R1....
4.
Chen Y, Zhao L, Li Q, Wheeler D, Varghese Z, Moorhead J, et al.
Nephrol Dial Transplant
. 2014 Jun;
29(10):1864-78.
PMID: 24895437
Background: Patients with chronic kidney disease (CKD) are unlikely to gain the same benefit from conventional doses of statins as do patients with cardiovascular disease alone. This study investigated whether...
5.
Chen Y, Ku H, Zhao L, Wheeler D, Li L, Li Q, et al.
Arterioscler Thromb Vasc Biol
. 2013 Nov;
34(2):365-76.
PMID: 24233489
Objective: The risk of cardiovascular disease is increased by up to 33 to 50× in chronic inflammatory states and convention doses of statins may not provide the same cardiovascular protection...
6.
Wu Y, Wu T, Wu J, Zhao L, Li Q, Varghese Z, et al.
J Endocrinol
. 2013 Sep;
219(3):195-204.
PMID: 24029730
Inflammatory stress is closely related to metabolic disease and insulin resistance. The precise cellular mechanism linking obesity and diabetes is largely unknown, but about 14-20% of obese individuals develop diabetes....
7.
Xu Z, Chen Y, Huang A, Varghese Z, Moorhead J, Yan F, et al.
Am J Physiol Renal Physiol
. 2011 Jul;
301(4):F713-22.
PMID: 21795641
Both lipids and inflammation play important roles in the progression of kidney disease. This study was designed to investigate whether inflammation exacerbates lipid accumulation via LDL receptors (LDLr), thereby causing...
8.
Mei M, Zhao L, Li Q, Chen Y, Huang A, Varghese Z, et al.
Lipids Health Dis
. 2011 Jul;
10:110.
PMID: 21718499
Background: Chronic systemic inflammation and abnormal free fatty acid metabolism are closely related to ectopic lipid deposition. In this study, we investigate if inflammation tissue-specifically disrupts lipogenesis and lipolysis in...
9.
Yuan Y, Zhao L, Chen Y, Moorhead J, Varghese Z, Powis S, et al.
Am J Physiol Renal Physiol
. 2011 Apr;
301(1):F236-43.
PMID: 21511699
Advanced glycation end products (AGEs) is one of the causative factors of diabetic nephropathy, which is associated with lipid accumulation in glomeruli. This study was designed to investigate whether N(ε)-(carboxymethyl)...
10.
Stanescu H, Arcos-Burgos M, Medlar A, Bockenhauer D, Kottgen A, Dragomirescu L, et al.
N Engl J Med
. 2011 Feb;
364(7):616-26.
PMID: 21323541
Background: Idiopathic membranous nephropathy is a major cause of the nephrotic syndrome in adults, but its etiologic basis is not fully understood. We investigated the genetic basis of biopsy-proven cases...